<i>DORNRÖSCHEN</i>is a direct target of the auxin response factor MONOPTEROS in the<i>Arabidopsis</i>embryo

Cole, Melanie; Chandler, John W.; Weijers, Dolf; Jacobs, Bianca; Comelli, Petra; Werr, Wolfgang

doi:10.1242/dev.032177

Cited by 160 publications

(175 citation statements)

References 51 publications

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“…3H). Similarly, the weak loss-of-function mp S319 mutant (22) exhibited zones of ectopic pericycle cell division, although they were less pronounced (Fig. 3I).…”

Section: Bdl-mp-dependent Auxin Response Module Acts In Lateral Rootmentioning

confidence: 90%

Bimodular auxin response controls organogenesis in Arabidopsis

Smet

Lau

Voß

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

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Like animals, the mature plant body develops via successive sets of instructions that determine cell fate, patterning, and organogenesis. In the coordination of various developmental programs, several plant hormones play decisive roles, among which auxin is the best-documented hormonal signal. Despite the broad range of processes influenced by auxin, how such a single signaling molecule can be translated into a multitude of distinct responses remains unclear. In Arabidopsis thaliana , lateral root development is a classic example of a developmental process that is controlled by auxin at multiple stages. Therefore, we used lateral root formation as a model system to gain insight into the multifunctionality of auxin. We were able to demonstrate the complementary and sequential action of two discrete auxin response modules, the previously described SOLITARY ROOT/INDOLE-3-ACETIC ACID (IAA)14-AUXIN REPONSE FACTOR (ARF)7-ARF19–dependent lateral root initiation module and the successive BODENLOS/IAA12-MONOPTEROS/ARF5–dependent module, both of which are required for proper organogenesis. The genetic framework in which two successive auxin response modules control early steps of a developmental process adds an extra dimension to the complexity of auxin’s action.

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“…3H). Similarly, the weak loss-of-function mp S319 mutant (22) exhibited zones of ectopic pericycle cell division, although they were less pronounced (Fig. 3I).…”

Section: Bdl-mp-dependent Auxin Response Module Acts In Lateral Rootmentioning

confidence: 90%

Bimodular auxin response controls organogenesis in Arabidopsis

Smet

Lau

Voß

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

Self Cite

269

234

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Section: Activation Of Esr1 Expression By Auxin and Cytokininmentioning

confidence: 99%

“…Previous studies have shown that the auxininducible transcription factor ARF5/MONOPTEROS (MP) binds the ESR1/DRN promoter and activates its expression during embryonic development (Cole et al, 2009). The ESR1/DRN promoter possesses two canonical auxin-responsive elements where ARF5/MP binds in vivo, and mutations in these sequences alter auxin-induced expression of ESR1/DRN in developing embryos (Cole et al, 2009). Interestingly, the expression of ARF5/MP is strongly upregulated in explants cultured on CIM and SIM (Che et al, 2006), raising the possibility that ARF5/MP might participate in auxin-induced ESR1 expression in cultured explants.…”

Section: Activation Of Esr1 Expression By Auxin and Cytokininmentioning

confidence: 99%

WIND1 Promotes Shoot Regeneration through Transcriptional Activation of ENHANCER OF SHOOT REGENERATION1 in Arabidopsis

et al. 2016

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Many plant species display remarkable developmental plasticity and regenerate new organs after injury. Local signals produced by wounding are thought to trigger organ regeneration but molecular mechanisms underlying this control remain largely unknown. We previously identified an AP2/ERF transcription factor WOUND INDUCED DEDIFFERENTIATION1 (WIND1) as a central regulator of wound-induced cellular reprogramming in plants. In this study, we demonstrate that WIND1 promotes callus formation and shoot regeneration by upregulating the expression of the ENHANCER OF SHOOT REGENERATION1 (ESR1) gene, which encodes another AP2/ERF transcription factor in Arabidopsis thaliana. The esr1 mutants are defective in callus formation and shoot regeneration; conversely, its overexpression promotes both of these processes, indicating that ESR1 functions as a critical driver of cellular reprogramming. Our data show that WIND1 directly binds the vascular system-specific and wound-responsive cis-element-like motifs within the ESR1 promoter and activates its expression. The expression of ESR1 is strongly reduced in WIND1-SRDX dominant repressors, and ectopic overexpression of ESR1 bypasses defects in callus formation and shoot regeneration in WIND1-SRDX plants, supporting the notion that ESR1 acts downstream of WIND1. Together, our findings uncover a key molecular pathway that links wound signaling to shoot regeneration in plants.

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“…Recently, it was shown that DORNRÖ SCHEN (DRN) is such a direct target (Chandler et al 2007;Cole et al 2009). DRN encodes an AP2-type transcription factor and acts redundantly with its paralog DRN-like (DRNL) in cotyledon development.…”

Section: Role Of Auxin In Shoot Meristem Formation and Cotyledon Formmentioning

confidence: 99%