Cinnamomum zeylanicum Essential Oil Formulation with Poly(propylene imine) Dendrimers with Surface-Grafted Glycerol: Release Kinetics of trans-Cinnamaldehyde and Germination Inhibition Effects

Abstract

The Third-generation glycerodendrimer polypropylenimine (GD-PPI-3) can be used in an aqueous formulation of Cinnamomum zeylanicum essential oil (CEO). The purpose was to give an overview of this innovative method of retaining and releasing essential oils. The formulation consisted of 366 min stirring at 1735 rpm of the aqueous solution of 2 mM GD-PPI-3 with CEO. Some physicochemical properties of these formulations, as well as the release of trans-cinnamaldehyde, have been studied. A bimodal distribution and no concentration or aging effect were observed by optical microscopy. Moreover, the release kinetics showed the retention of volatile molecules in solution under various environmental conditions. The release profile was characterized by an initial burst followed by a steady release. The dendrimers allowed us to reduce this initial burst and extended the release by at least 15 h. In addition, the herbicidal effect was evaluated: inhibition of Arabidopsis thaliana seed germination was obtained for 7 days with a formulation of 12.5 mg/L CEO in a closed space and 360 mg/L CEO in an open space.

Cinnamaldehyde-Contained Polymers and Their Biomedical Applications

“…Cinnamon essential oil, one of the most popular researched plant essential oils, can often be extracted from various plant parts (e.g., bark and leaf) of several trees of the genus Cinnamomum , and has been applied in food, cosmetics, and other fields due to its unique aroma and excellent antibacterial activity [ 3 , 4 , 5 ]. However, the complex composition of cinnamon essential oil makes it difficult to control the consistency of its composition and bioactivity, thus limiting its application.…”