2016
DOI: 10.1136/bcr-2016-214486
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Chryseobacterium indologenes: an emerging infection in the USA

Abstract: Nursing home-associated infections and antibiotic resistant pathogens constitute common and serious problems in the geriatric population.Chryseobacterium indologenes, a non-motile Gram-negative rod, though widely distributed in nature, is an uncommon human pathogen. Typically thought of as an organism of low virulence, it may cause serious infections, particularly among the immunocompromised. The majority of reported cases are nosocomial, often associated with immunosuppression or indwelling catheters. It has … Show more

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Cited by 48 publications
(36 citation statements)
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“…Work is ongoing to analyze the functional significance of the D. japonica microbiome, but we predict that shifts in the ratio of Proteobacteria and Bacteroidetes may also impact D. japonica growth and development. Chryseobacterium , which was enriched in space‐exposed worms, is a widespread genus of bacteria, with some species being rare pathogens in humans (Mukerji, Kakarala, Smith, & Kusz, ) and others providing benefits to animal and plant hosts through improved growth and pathogen protection (Antwis, Preziosi, Harrison, & Garner, ; Coon, Vogel, Brown, & Strand, ). Future efforts will elucidate the functional consequences of Chryseobacterium and other D. japonica bacteria.…”
Section: Discussionmentioning
confidence: 99%
“…Work is ongoing to analyze the functional significance of the D. japonica microbiome, but we predict that shifts in the ratio of Proteobacteria and Bacteroidetes may also impact D. japonica growth and development. Chryseobacterium , which was enriched in space‐exposed worms, is a widespread genus of bacteria, with some species being rare pathogens in humans (Mukerji, Kakarala, Smith, & Kusz, ) and others providing benefits to animal and plant hosts through improved growth and pathogen protection (Antwis, Preziosi, Harrison, & Garner, ; Coon, Vogel, Brown, & Strand, ). Future efforts will elucidate the functional consequences of Chryseobacterium and other D. japonica bacteria.…”
Section: Discussionmentioning
confidence: 99%
“…The majority of reported human infections have been from Asia. Only <10% reports have come from Australia, Europe and the USA 5. Chryseobacteria are thought to have low pathogenicity with unclear virulence factors but they can produce biofilms on medical implants, and possess protease activity that may help these pathogens in causing invasive infections in hospitalised patients with multiple comorbid illnesses (such as malignancy, chronic kidney disease, hypertension and diabetes) and indwelling vascular catheters 6–8…”
Section: Discussionmentioning
confidence: 99%
“…E. meningoseptica predominately causes outbreaks of meningitis in immunocompromised patients, particularly in premature newborns and infants in neonatal intensive care units of developing countries. [4] The bacterium is a rare cause of nosocomial pneumonia, endocarditis, and meningitis in immunocompromised adults. Recently in the past few years, it has been found to cause soft tissue infection and sepsis in immunocompetent adults.…”
Section: Introductionmentioning
confidence: 99%