<i>           Banned: A History of Pesticides and the Science of Toxicology.         </i>            By            Frederick Rowe Davis            .            New Haven           :            Yale University Press           ,            2014           .            288            pp. Illustrations, tables, notes, and index. Cloth $40.00.

Polycystic ovarian syndrome (PCOS) is the most frequent endocrine disorder currently plaguing women. There are many factors associated with high androgenicity in the female body. Dysbiosis of gut microbiota may be one of the primary reasons that initiate PCOS. Emerging evidence suggests that some plastics, pesticides, synthetic fertilizers, electronic waste, food additives, and artificial hormones that release endocrine-disrupting chemicals (EDCs) cause microbial Dysbiosis. It is reported that the permeability of the gut is increased due to an increase of some Gram-negative bacteria. It helps to promote the lipopolysaccharides (LPS) from the gut lumen to enter the systemic circulation resulting in inflammation. Due to inflammation, insulin receptors' impaired activity may result in insulin resistance (IR), which could be a possible pathogenic factor in PCOS development. Good bacteria produce short-chain fatty acids (SCFAs), and these SCFAs have been reported to increase the development of Mucin-2 (MUC-2) mucin in colonic mucosal cells and prevent the passage of bacteria. Probiotic supplementation for PCOS patients enhances many biochemical pathways with beneficial effects on changing the colonic bacterial balance. This way of applying probiotics in the modulation of the gut microbiome could be a potential therapy for PCOS.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Banned: A History of Pesticides and the Science of Toxicology. By Frederick Rowe Davis . New Haven : Yale University Press , 2014 . 288 pp. Illustrations, tables, notes, and index. Cloth $40.00.

Cited by 2 publications

References 0 publications

Green Nanoparticles for Biomedical and Bioengineering Applications

Green Nanoparticles for Biomedical and Bioengineering Applications

Probiotics as Potential Remedy for Restoration of Gut Microbiome and Mitigation of Polycystic Ovarian Syndrome

Contact Info

Product

Resources

About