AnmO₂l: An open-source pulse-dose oxygen conserving device for the COVID-19 crisis

Abstract

The surge of COVID-19 cases in India and around the world has resulted in acute oxygen shortage. Oxygen therapy through nasal cannula with flow rates of 1-6 L/min is an effective treatment for many COVID-19 patients in non-critical conditions and may help prevent disease progression. The same treatment is also used in post-acute care for recovering COVID-19 patients. Here we describe a simple, open source, and rapidly manufacturable oxygen conservation device for use with dual-port nasal cannula that can extend the life of current oxygen supply by almost two to three times, which we hope will help towards coping with the ongoing crisis. We estimate the bill of materials cost to be under $50 for manufacturing in bulk.

Collaborative Use of Lung Mechanics Simulation for Testing and Iterative Design for Three Emergency Use Ventilation Device Projects

“…We experienced firsthand the power of such collaboration to rapidly iterate the design, development, and bench testing of 3 ventilation devices in only a few months. Our lung simulation team continued to collaborate with one group on a later project, providing advice on developing an oxygen-conserving noninvasive oxygen delivery device 26 …”