I-131 false positive uptake in a huge parapelvic renal cyst

Kraft, Otakar; Sirucek, Pavel; Mrhac, Lubomir; Havel, Martin

doi:10.5603/nmr.2011.0008

Cited by 15 publications

(11 citation statements)

References 4 publications

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“…There are many reported cases of false-positive radioiodine uptake in tissues other than ovary, such as bone tissue [ 8 ], hepatic hydatid cyst [ 9 ] and parapelvic renal cyst [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria

Almohamad

Ahmad

et al. 2018

Journal of Surgical Case Reports

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Iodine has always been connected to thyroid gland, and the fact that thyroid tissue traps, organificates and stores iodine more than other tissues is well known, hence the use of radioiodine as a diagnostic and therapeutic tool for thyroid disorders. However, false-positive cases do occur. We present a case of a 34-year-old patient who underwent total thyroidectomy for papillary carcinoma. Results of follow up TSH, thyroglobulin and thyroglobulin antibody tests after surgery lead to two rounds of radioactive iodine. After that, a radioiodine whole-body scan showed high uptake in the pelvis above bladder. Computed tomography scan showed a pelvic heterogeneous mass with some calcifications. Surgical removal and subsequent pathology confirmed the absence of metastasis. The final pathological diagnosis was serous cystadenoma, endometriosis cyst and leiomyoma. As the real cause behind false-positive iodine uptake by these tissues has yet to be determined, careful assessment should be considered in any suspicious case.

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“…There are many reported cases of false-positive radioiodine uptake in tissues other than ovary, such as bone tissue [ 8 ], hepatic hydatid cyst [ 9 ] and parapelvic renal cyst [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria

Almohamad

Ahmad

et al. 2018

Journal of Surgical Case Reports

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“…A pyelocalyceal diverticulum [5], or a cyst [6] of the kidney can be the source of the uptake. Also a leiomyoma of the uterus [7] is another cause for false negative images.…”

Section: Discussionmentioning

confidence: 99%

A Rare Pitfall of I-131 Post-Ablative Scan

Durak¹

2014

Thyroid Disorders Ther

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“…Examples include cystic and pouch-like structures such as nasolacrimal sac cyst [37], esophageal diverticulum [38][39][40], epiphrenic diverticulum [41], pleuropericardial cyst [42], bronchogenic cyst [43,44], thymic cyst (Fig. 4) [45,46], breast cyst [47], Meckel's diverticulum [48], appendix [49], pelvocalyceal diverticulum [50,51], hepatic cyst [52][53][54], renal cyst [55][56][57][58], retroperitoneal cyst [59 • ], ovarian cyst [60,61], nabothian cyst [62], sebaceous cyst [63,64], and epithelial cyst [65]. Arterial dilation leading to stasis of blood flow has also been shown to have false-positive RAI retention [66,67].…”

Section: Radioiodinated Bodily Fluid Retentionmentioning

confidence: 99%

Causes of False-Positive Radioactive Iodine Uptake in Patients with Differentiated Thyroid Cancer

Ozomaro

Flavell

et al. 2021

Curr Radiol Rep

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Purpose Radioactive iodine (RAI) whole-body scan is a sensitive imaging modality routinely used in patients with differentiated thyroid cancer to detect persistent and recurrent disease. However, there can be false-positive RAI uptake that can lead to misdiagnosis and misclassification of a patient’s cancer stage. Recognizing the causes of false positivity can avoid unnecessary testing and treatment as well as emotional stress. In this review, we discuss causes and summarize various mechanisms for false-positive uptake. Recent Findings We report a patient with differentiated thyroid cancer who was found to have Mycobacterium avium complex infection as the cause of false-positive RAI uptake in the lungs. Using this case example, we discuss and summarize findings from the literature on etiologies of false-positive RAI uptake. We also supplement additional original images illustrating other examples of false RAI uptake. Summary False-positive RAI uptake may arise from different causes and RAI scans need to be interpreted in the context of the patient’s history and corresponding cross-sectional imaging findings on workup. Understanding the potential pitfalls of the RAI scan and the mechanisms underlying false uptake are vital in the care of patients with differentiated thyroid cancer.

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I-131 false positive uptake in a huge parapelvic renal cyst

Cited by 15 publications

References 4 publications

False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria

False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria

A Rare Pitfall of I-131 Post-Ablative Scan

Causes of False-Positive Radioactive Iodine Uptake in Patients with Differentiated Thyroid Cancer

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