“…Numerous methods have been proposed to assess early and accurate the diagnosis of the types of lesion in such brain damage including electroencephalography [1], biochemical markers [2,18], cranial ultrasound [1,3,4,19,20], computed tomography [21,22], and MRI [5,15,23]. Transient periventricular echo densities or periventricular leukomalacia are predictive of impaired neurodevelopmental outcome [1,3,4,[24][25][26] as well as ventricular dilatation and cerebral atrophy [19].…”