Hypoxia and the Fat Embolism Syndrome [Summary]

Early onset fat embolism syndrome: Case report and literature review

“…3,4,16 The syndrome may present across a spectrum from subclinical features to a fulminant course, including a cerebral form, which carries higher mortality. 10,11,16,19 The incidence is said to be higher in closed compared to open fractures. 6 Our patient had a closed fracture.…”

“…1,3,[5][6][7][8]10,19 Neurological manifestations may vary from altered sensorium to focal and generalised encephalopathy with sensory deficits. Early neurological changes may be detected on a DWMRI scan in patients who do not present with the other typical manifestations.…”

“…[5][6][7]10,19 The role of steroids is controversial and may have a role in the late phase, but has only been shown to be of benefit if given prior to the event, 8,10 which is impractical in cases of trauma. Our patient responded slowly to the supportive care in the ICU and the prolonged ICU stay is related to her neurological sequelae that blunted her affect.…”