Hypospadias in Istanbul: Incidence and risk factors

Akın, Yasemin; Ercan, Oya; Telatar, Berrin; Tarhan, Fatih; Çömert, Serdar

doi:10.1111/j.1442-200x.2011.03340.x

Cited by 25 publications

(26 citation statements)

References 49 publications

(294 reference statements)

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“…The most common associated anomalies in boys with hypospadias are cryptorchidism and inguinal hernia, present in about 8%–10% and 9%–15% of these patients, respectively 24. In addition, 17.6% of hypospadiac boys in Istanbul were found to have malformations of the genital or inguinal region 25. Our results were in good agreement with these previous findings.…”

Section: Discussionsupporting

confidence: 92%

Risk factors for hypospadias in China

Liang

Lipianskaya

et al. 2014

Asian J Androl

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This case-controlled study was designed to evaluate the association between various baseline parental factors and the risk of hypospadias in China. Patients were selected from tertiary referral hospitals in Anhui, a province in mid-eastern China. A questionnaire was given to the parents of each patient. The final database included 193 cases and 835 controls. The incidence of additional coexistent anomalies was 13.0%, primarily cryptorchidism (9.8%). Ten patients (5.1%) were from families with genital anomaly, including five families (2.6%) with hypospadias. The risks of hypospadias was higher for children of mothers > 35 (odds ratio [OR] =1.47) and < 18 (OR = 2.95) years of age, and in mothers who had consumed alcohol (OR = 2.67), used drugs (OR = 1.53) and had an infection (OR = 1.87) during pregnancy. The risk of hypospadias was also higher when mothers (OR = 1.68) and fathers (OR = 1.74) were engaged in agriculture. Other factors assessed were not associated with the risk of hypospadias.

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Section: Discussionsupporting

confidence: 92%

Risk factors for hypospadias in China

Liang

Lipianskaya

et al. 2014

Asian J Androl

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“…Akin et al [19] observed positive family history in patients with hypospadias in 26.5% cases in their study in Turkey. Abdelrahman et al [20] also observed 12% hypospadias patients with positive family history for this condition.…”

Section: Discussionmentioning

confidence: 87%

“…In contrast to 2.8% patients with hypospadias associated with cryptorchidism, Akin et al [19] reported 14.7% patients of hypospadias with cryptorchidism. Abdelrahman et al [20] observed this positive relationship between hypospadias and cryptorchidism in 20%.…”

Section: Discussionmentioning

confidence: 99%

Hypospadias Repair: A Single Centre Experience

Khan

Majeed

Hayat

et al. 2014

Plastic Surgery International

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Objectives. To determine the demographics and analyze the management and factors influencing the postoperative complications of hypospadias repair. Settings. Hayatabad Medical Complex Peshawar, Pakistan, from January 2007 to December 2011. Material and Methods. All male patients presenting with hypospadias irrespective of their ages were included in the study. The data were acquired from the hospital's database and analyzed with Statistical Package for Social Sciences (SPSS). Results. A total of 428 patients with mean age of 8.12 ± 5.04 SD presented for hypospadias repair. Midpenile hypospadias were the most common. Chordee, meatal abnormalities, cryptorchidism, and inguinal hernias were observed in 74.3%, 9.6%, 2.8%, and 2.1% cases, respectively. Two-stage (Bracka) and TIP (tubularized incised urethral plate) repairs were performed in 76.2% and 20.8% of cases, respectively. The most common complications were edema and urethrocutaneous fistula (UCF). The complications were significantly lower in the hands of specialists than residents (P-value = 0.0086). The two-stage hypospadias repair resulted in higher complications frequency than single-stage repair (P value = 0.0001). Conclusion. Hypospadias surgery has a long learning curve because it requires a great deal of temperament, surgical skill and acquaintance with magnifications. Single-stage repair should be encouraged wherever applicable due to its lower postoperative complications.

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“…İngiltere'de 1993 ile 2000 yılları arasında 3.1/1000 oranında iken, Quebec, Kanada'da 11.4/1000 sıklıkta görülmüştür (19,20) . Ülkemizde İstanbul'da yapılan bir çalışmada, bu oran 19.4/1000 olarak saptanmıştır (21) . Yine de tanı koymada ve veri analizindeki farklılıklar bu konuda yorum yapmayı güçleştirmektedir.…”

Section: üRetra Ve Hipospadiasunclassified

The role of hormones and environmental factors in the development of genitourinary anomalies

Özel¹

2016

TCCD

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Öz Çevresel faktörler antenatal hayattan itibaren insanın geli 134-140, 2016134-140, doi:10.5222/JTAPS.2016 İnsanoğlu dünyaya gelmeden daha anne karnında bulunduğu çevre ile iletişimine başlar. Başlangıçta büyüme ve gelişme üzerine kurduğu bu ilişki zamanla beraber yaşama uyum ve anlayışına yerini bırakır. Hormonlar ise bu işleyişi belirli bir düzene koyarak yaşam süregenliğinin uygun şekilde devam etmesini sağlar. Bu açıdan bakıldığında insanın bulunduğu çevre ile beraber düşünülmesi ve çoğu oluşan sağlık sorunlarının temelinde yaşadığı çevre koşullarının da göz önünde bulundurulması en akılcı yaklaşımdır. Çevresel faktörleri şu şekilde sınıflan-dırmak olasıdır: Bu derlemenin amacı aynı zamanda çevre sağlığı bilincinin tarihsel gelişimi içindegenitoüriner sistem odak alınarak hormonlar ile çevresel faktörlerin etkileşimi ile oluşan anomalilerin değerlendirilmesidir.Modern yaşamın bir parçası olan kimyasalların insan bedeni üzerinde çok farklı etkileri bulunmaktadır. İnsan vücudunda homeostazisi etkileyen, gelişme ve

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Hypospadias in Istanbul: Incidence and risk factors

Abstract: Genetic predisposition and placental insufficiency in early gestation might play a role in the etiology of hypospadias.

Cited by 25 publications

References 49 publications

Risk factors for hypospadias in China

Risk factors for hypospadias in China

Hypospadias Repair: A Single Centre Experience

The role of hormones and environmental factors in the development of genitourinary anomalies

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