Hypomagnesemia

Agus, Zalman S.

doi:10.1681/asn.v1071616

Cited by 236 publications

(37 citation statements)

References 44 publications

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“… 11 The kidneys respond to magnesium depletion by decreasing urinary magnesium excretion to very low levels. Therefore, daily excretion higher than 10-30 mg or fractional excretion above 2% is indicative inadequate renal loss of magnesium 12 . Our patient presented urinary levels of magnesium greater than 70% of the filtered load.…”

Section: Discussionmentioning

confidence: 99%

Polymyxin Acute Kidney Injury: a case of severe tubulopathy

Goldin

Silva

et al. 2022

Braz. J. Nephrol.

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Polymyxins are antibiotics developed in the 1950s. Polymyxin-induced neurotoxicity has been often described in medical literature. The same cannot be said of nephrotoxicity or tubulopathy in particular. This report describes the case of a patient prescribed polymyxin B to treat a surgical wound infection, which led to significant increases in fractional excretion of calcium, magnesium, and potassium and subsequent persistent decreases in the levels of these ions, with serious consequences for the patient. Severe hypocalcemia, hypomagnesemia, and hypokalemia may occur during treatment with polymyxin. Calcium, magnesium and potassium serum levels must be monitored during treatment to prevent life-threatening conditions.

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Section: Discussionmentioning

confidence: 99%

Polymyxin Acute Kidney Injury: a case of severe tubulopathy

Goldin

Silva

et al. 2022

Braz. J. Nephrol.

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“…Although the mechanism is not clear, magnesium is believed to equalize repolarization. Furthermore, some reports have found a correlation between Mg and QT dispersion [ 9 ]. In the present case, hypomagnesemia was observed on postoperative examination.…”

Section: Discussionmentioning

confidence: 99%

Ventricular fibrillation during carotid endarterectomy and bailout stenting: a case report

et al. 2022

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Background Carotid artery manipulation is not a special technique but reports of intraoperative ventricular fibrillation are rare. The risk of fatal arrhythmias may be hidden behind routine surgical techniques and anesthetic management. We focused on QT prolongation and QT dispersion. Case presentation A 77-year-old man underwent carotid endarterectomy and bailout stenting. Although there were no obvious preoperative risk factors for intraoperative ventricular tachyarrhythmia, ventricular fibrillation (VF) had occurred during a maneuver of the carotid artery under hypercapnia. QTc was prolonged from 317 ms before surgery to 458 ms before the onset of VF. QTc dispersion between leads II and III was also increased to 50 ms. Hypomagnesemia was noted after resuscitation by electrical defibrillation, adrenaline, and noradrenaline. Conclusions We considered that the combination of multiple risk factors led to the development of ventricular fibrillation. It should be noted that carotid artery manipulation has the potential to cause arrhythmias.

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“…Besides, hyperchloremia is closely related to metabolic acidosis, and may cause digestive complications [ 21 ]. Hypomagnesemia may lead to neuromuscular and cardiovascular complications and pathological calcium metabolism for its depression of nerve excitability [ 22 ]. The decrease of carbon dioxide capacity would indicate complications of respiratory alkalosis, leading to relative respiratory and acid–base disturbance [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Variations in postoperative electrolyte concentrations and influential factors in hip arthroscopy

Gao

Zhou

et al. 2022

BMC Musculoskelet Disord

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Background Different from arthroscopy in other joints, more perfusion is required for a better access to perform surgical procedures in hip arthroscopic operations. The significant fluid perfused may lead to complications of partial tissue injury and electrolyte imbalance. However, there were few studies on the change of serum electrolyte after hip arthroscopy and the influential factors were still unknown. Methods We evaluated consecutive patients who underwent hip arthroscopy in our hospital between October 2021 and February 2022. Age, sex, and BMI matched patients who underwent arthroscopic anterior cruciate ligament (ACL) reconstruction at the same time were also included as the control group. Preoperative and postoperative serum electrolyte of sodium (Na +), potassium (K +), chloride (Cl-), magnesium (Mg2 +), and carbon dioxide capacity (CO2CP) were analyzed. The correlations between influential factors like perfusion volume, operating time, BMI and hip circumference, and changes in serum electrolyte were also analyzed. Results A total of 79 patients were involved in this study, including 49 patients who underwent hip arthroscopy and 30 patients who underwent knee arthroscopy. For hip arthroscopy, decrease of potassium levels was observed in 40.8% of the patients, and postoperative hypokalemia was found in 10.2% patients. There were significant variations in postoperative sodium, magnesium, chloride and carbon dioxide capacity in hip arthroscopy (p < 0.05). No correlations were found between each of the electrolyte concentrations and influential factors like perfusion volume, operating time, BMI, sex and hip circumference. The significant variations were found in chloride and carbon dioxide capacity in knee arthroscopy (p < 0.05). Conclusions Hip arthroscopy would significantly influence postoperative serum electrolyte, and hypokalemia could be a postoperative complication. The correlation between serum electrolyte and fluid perfusion volume is remained to be investigated. We therefor advocate that performing a systematic care of preoperative and postoperative serum electrolyte analysis as perioperative management is necessary.

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Hypomagnesemia

Cited by 236 publications

References 44 publications

Polymyxin Acute Kidney Injury: a case of severe tubulopathy

Polymyxin Acute Kidney Injury: a case of severe tubulopathy

Ventricular fibrillation during carotid endarterectomy and bailout stenting: a case report

Variations in postoperative electrolyte concentrations and influential factors in hip arthroscopy

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