Hypokaliämische thyreotoxische periodische Paralyse (HTPP)

Abstract

Hypokalemic thyrotoxic periodic paralysis (HTPP), a subtype of hypokalemic paralysis, is unusual in Caucasians. In Asian men the disease is more common. The underlying mechanism is an extra-intracellular shift of potassium in the voluntary muscle cells. In contrast to hereditary autosomal dominant paralyses, a genetic defect is not known. Usually, symptoms of hyperthyreosis in HTPP are mild which can hamper the correct diagnosis.

Chest pain and paralysis after pulse prednisolone therapy an unusual case presentation of thyrotoxic periodic paralysis: a case report

“…Differential diagnosis of acute tetraparesis includes paraplegia caused by trauma, Guillain-Barré syndrome, ischemia, myasthenia gravis, inflammation, tumor, dissociative paralysis and periodic paralysis [1]. The heterogeneous group of muscle diseases known as periodic paralyses (PP) is characterized by episodic, sudden onset, flaccid paralysis of a single, several or all skeletal muscles with usually complete recovery between the attacks.…”