To be, or not to be… Guillain-Barré Syndrome

Florian, Ioan Alexandru; Lupan, Iulia; Sur, Lucia; Samaşcă, Gabriel

doi:10.1016/j.autrev.2021.102983

Cited by 14 publications

(10 citation statements)

References 274 publications

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“…In patients with a previous episode of GBS not associated with COVID-19, vaccination is recommended. However, age and risk factors must be considered [78,79]. We found no data about the safety or efficacy of SARS-CoV-2 vaccines in patients with a history of ADEM.…”

Section: Covid-19 Vaccination In Patients With Neuroimmune Disordersmentioning

confidence: 84%

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COVID-19 and autoimmune diseases of the nervous system — an update

Morawiec

Adamczyk

Adamczyk-Sowa

2023

Neurol Neurochir Pol.

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Introduction. Due to a similar pathomechanism, COVID-19 infection may significantly affect the course of autoimmune diseases (AIDs). In our review, we aimed to assess the severity of SARS-CoV-2 infection, response to treatment, and the impact of COVID-19 infection on the course of the underlying disease in patients with neuroimmune diseases.State of the art. In the time of the COVID-19 pandemic, it was important to determine the influence of COVID-19 infection on the course of autoimmune diseases due to the weakened immune system and immunosuppressive therapies.Clinical implications. Many reports have indicated that in patients with AIDs, the existence of the disease is not associated with a worse prognosis in the course of the viral infection. Patients in advanced stages of the disease, elderly patients, and those with comorbidities are at risk of more frequent hospitalisations and higher mortality in the course of COVID-19. Moreover, some drugs used in AIDs have been tested for their efficacy in SARS-CoV-2 infection. Episodes of newly diagnosed myasthenia gravis, Guillain-Barré syndrome, acute disseminated encephalomyelitis (ADEM), and neuromyelitis optica spectrum disorder (NMOSD) secondary to COVID-19 or vaccination have also been reported. Vaccination against this pathogen is highly recommended in most patients with AIDs. Future directions. Despite many studies on the association between COVID-19 and neuroimmune diseases, more specific data is needed. The approach to patients with AIDs should be individual, since many issues remain unresolved despite the long-lasting pandemic.

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Section: Covid-19 Vaccination In Patients With Neuroimmune Disordersmentioning

confidence: 84%

“…We found no data about the safety or efficacy of SARS-CoV-2 vaccines in patients with a history of ADEM. Some reports have shown cases of MG, GBS, NMOSD and ADEM following vaccination against SARS-CoV-2 [77][78][79][80][81][84][85][86]. Nevertheless, this should be interpreted with caution.…”

Section: Covid-19 Vaccination In Patients With Neuroimmune Disordersmentioning

confidence: 96%

COVID-19 and autoimmune diseases of the nervous system — an update

Morawiec

Adamczyk

Adamczyk-Sowa

2023

Neurol Neurochir Pol.

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“…Guillain Barré syndrome occurs upon demyelination of peripheral nerves (collagen type 6), and is often induced by an infection or a drug [ 27 ]. Guillain Barré shares clinical similarities with chronic inflammatory demyelinating polyneuropathy [ 28 ], and with peripheral neuropathies, such as POEMS, chronic inflammatory demyelinating polyneuropathy, and multifocal motor neuropathy, as shown in Figure 2 .…”

Section: Resultsmentioning

confidence: 99%

Autoimmune Disease Classification Based on PubMed Text Mining

Samuels

Malov

Saha

et al. 2022

JCM

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Autoimmune diseases (AIDs) are often co-associated, and about 25% of patients with one AID tend to develop other comorbid AIDs. Here, we employ the power of datamining to predict the comorbidity of AIDs based on their normalized co-citation in PubMed. First, we validate our technique in a test dataset using earlier-reported comorbidities of seven knowns AIDs. Notably, the prediction correlates well with comorbidity (R = 0.91) and validates our methodology. Then, we predict the association of 100 AIDs and classify them using principal component analysis. Our results are helpful in classifying AIDs into one of the following systems: (1) gastrointestinal, (2) neuronal, (3) eye, (4) cutaneous, (5) musculoskeletal, (6) kidneys and lungs, (7) cardiovascular, (8) hematopoietic, (9) endocrine, and (10) multiple. Our classification agrees with experimentally based taxonomy and ranks AID according to affected systems and gender. Some AIDs are unclassified and do not associate well with other AIDs. Interestingly, Alzheimer’s disease correlates well with other AIDs such as multiple sclerosis. Finally, our results generate a network classification of autoimmune diseases based on PubMed text mining and help map this medical universe. Our results are expected to assist healthcare workers in diagnosing comorbidity in patients with an autoimmune disease, and to help researchers in identifying common genetic, environmental, and autoimmune mechanisms.

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“…It is well known that vaccinations elicit a strong immunologic response to establish long-term protective immunity within the host 12 . Oftentimes, vaccine administration can trigger a wide spectrum of adverse reactions, many of which are exacerbated by various factors inherent to the host, including age, gender, immunocompromise, body mass index, and baseline health status and comorbidities (e.g., cardiovascular disease) 13 .…”

Section: Discussionmentioning

confidence: 99%

Bell Palsy and Parsonage-Turner Syndrome Following Pneumococcal Vaccination: A Case Report

Maez,

Pierce,

Richter

2024

JBJS Journal of Orthopaedics for Physician Assistants

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Parsonage-Turner syndrome (PTS), also known as brachial neuritis, is a rare self-limiting, idiopathic condition characterized by sudden onset upper extremity pain with associated weakness and muscle atrophy. There exists a growing association between the development of PTS and infection/vaccinations in recent years. No case of PTS has been documented following pneumococcal vaccination to date. Bell palsy (BP) is an idiopathic disease process involving acute-onset unilateral acute facial paralysis resulting from edema and inflammation of the seventh cranial nerve. The etiology of BP is also largely unknown, but infectious processes, including viral reactivation and adverse vaccination reactions, have recently been documented. Although both PTS and BP are uncommon on their own, it is extremely rare for the 2 conditions to occur simultaneously. This case report presents a unique case of PTS and BP developing following the administration of the pneumococcal 20-valent conjugate vaccine.

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To be, or not to be… Guillain-Barré Syndrome

Cited by 14 publications

References 274 publications

COVID-19 and autoimmune diseases of the nervous system — an update

COVID-19 and autoimmune diseases of the nervous system — an update

Autoimmune Disease Classification Based on PubMed Text Mining

Bell Palsy and Parsonage-Turner Syndrome Following Pneumococcal Vaccination: A Case Report

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