Hypoglycemia — A Complication of Hemodialysis

Rigg, Gerald; Bercu, Bernard A.

doi:10.1056/nejm196711232772109

Cited by 28 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[46] concerning recurrent and fatal hypoglycemia in a patient with chronic renal failure, suggests that this problem may be more frequent than was previously recognized. Hypoglycemia has also occurred as a complication of peritoneal [51] and hemodialysis [52,114], and points to the necessity of monitoring blood glucose concentrations in the immediate postdialysis period.…”

Section: Hypoglycemia In Renal Failurementioning

confidence: 99%

Insulin and the Kidney

Rubenstein

Mako

Horwitz

1975

Nephron

View full text Add to dashboard Cite

Changes in renal function and structure are frequently observed in patients with diabetes mellitus. In the early phases of the disease, alterations in glomerular filtration rate, renal plasma flow, glomerular permeability and tubular capacity for glucose reabsorption occur. In the late stages of juvenile onset diabetes, renal failure is a common cause of death. For this reason, increasing attention is being paid to the possibility of long-term dialysis and renal transplantation in these patients. The kidneys play an important role in regulating insulin metabolism. The renal arteriovenous difference is approximately 30–45% and a linear relationship exists between the arterial insulin level and the renal arteriovenous concentration difference. The renal extraction of insulin is 200 ml/min in man, and it is estimated that 6–8 U are removed and degraded by the kidney in 24 h. The quantity of insulin in urine is small. However, its clearance is relatively constant over a wide range of serum concentrations and is 0.15–0.5 ml/min. The mean basal insulin excretion is 3.6 µU/mg creatinine, and a fourfold rise occurs following a glucose load. The urinary insulin values in neonates, children and patients with diabetes and renal failure are reviewed. In diabetic patients, progressive renal disease is accompanied by decreasing insulin requirements. In contrast, nondiabetic patients who develop renal failure frequently show abnormalities in carbohydrate metabolism, the commonest of which is a pseudodiabetic state.

show abstract

Section: Hypoglycemia In Renal Failurementioning

confidence: 99%

Insulin and the Kidney

Rubenstein

Mako

Horwitz

1975

Nephron

View full text Add to dashboard Cite

show abstract

“…Hypoglycemia (66) and hyponatremia (67) have also been suggested as causes for disequilibrium, but there is little evidence that hypoglycemia plays any significant role in this, although the mild hyponatremia associated with use of dialysate of low sodium concentration may playa minor role.…”

Section: : Acute Complications With Hemodialysis 753mentioning

confidence: 99%

Acute Complications Associated With Hemodialysis

Blagg¹

1989

Replacement of Renal Function by Dialysis

View full text Add to dashboard Cite

“…White and Kurtzman (1971) reported the case of a non-diabetic azotaemic patient who developed symptomatic hypoglycaemia on three different occasions after peritoneal dialysis. Two reports (Gutman et al, 1967;Rigg and Bercu, 1967) described hypoglycaemia occurring after haemodialysis with high dialysis bath glucose concentrations.…”

Section: Commentmentioning

confidence: 99%

Fatal hypoglycaemia occurring after peritoneal dialysis.

Greenblatt¹

1972

BMJ

View full text Add to dashboard Cite

Hypoglycemia — A Complication of Hemodialysis

Cited by 28 publications

References 5 publications

Insulin and the Kidney

Insulin and the Kidney

Acute Complications Associated With Hemodialysis

Fatal hypoglycaemia occurring after peritoneal dialysis.

Contact Info

Product

Resources

About