Hypocalcemia Induced Rhabdomyolysis and Acute Renal Failure After Thyroidectomy: A Case Report

Abstract

Rhabdomyolysis is a potentially life-threatening syndrome resulting from the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. We report a case of a 24-year-old woman with hypocalcemia which occured after a thyroidectomy operation. This hypocalcemia was severe enough to cause convulsion, rhabdomyolysis and acute renal failure. The reason of severe hypocalcemia in our case may be multifactorial; hypoparathyroidism, rhabdomyolysis and acute renal failure. The development of hypocalcemia, convulsion attacks, rhabdomyolysis and acute renal failure occurring in the patient after iatrogenic hypoparathyroidism has rendered the case interesting due to the rarity of such developments.

Severe Hypokalemia-Associated Rhabdomyolise and Unusual Poliuria in Patient with Primary Aldosteronism

“…Routine biochemistry findings are not generally diagnostic in hypertensive patients but hypokalemia with metabolic alkalosis and serum sodium levels close to high-normal should remind one of PA (8). In PA diagnosis, the following criterias support the diagnosis: 1-Plasma aldosteron/ renin ratio > 30 and plasma aldosterone level > 25 ng/ dl provide a sensitivity 90% and a specificity 91% for the diagnosis of primary aldosteronizm (9), 2-No aldosterone suppression in sodium loading test, 3-Unilateral adenoma that is detected with high-resolution computed tomography (HRCT) (10). The case was presented because of severe hypokalemia and associated rhabdomyolisis development and extraordinary polyuria development about 19 L/day.…”