Hypertrophic (Verrucous) Cutaneous Lupus Erythematosus of the Lip and Oral Cavity: A Series of 4 Cases

Nico, Marcello Menta Simonsen; Lourenço, Sílvia Vanessa

doi:10.2340/00015555-1433

Cited by 8 publications

(9 citation statements)

References 10 publications

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“…Nico et al (2014) reviewed different aspects of lip involvement in LE in a comprehensive article and concluded that the extension of LE lesions from the vermilion to the skin is a distinctive feature that is frequently seen in labial LE. Severe scarring may also be problematic with this disease (Nico et al, 2014, Nico and Lourenço, 2013). Multiple blisters along the vermilion were also considered a symptom of bullous LE (Nico et al, 2014, Nico and Lourenço, 2012).…”

Section: Discussionmentioning

confidence: 99%

Persistent lip enlargement: An unusual presentation of lupus erythematosus

Nikoo

Daneshpazhooh

Fahim

et al. 2017

International Journal of Women's Dermatology

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Macrocheilia is a challenging problem with a variety of underlying causes that are both local and systemic, and granulomatous causes underlie the majority of cases. In this study, we report on a 31-year old man who presented with a chronic lower lip enlargement and a nodular submental erythematous lesion. He was otherwise clinically healthy. Laboratory test results were within the normal limit except for a positive anti-double stranded DNA test result. A diagnosis of cutaneous lupus erythematosus was made on the basis of histopathology and direct immunofluorescence. The lesions resolved dramatically after treatment with hydroxychloroquine. Lupus erythematosus should be considered when examining patients who present with chronic lip swelling.

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Section: Discussionmentioning

confidence: 99%

Persistent lip enlargement: An unusual presentation of lupus erythematosus

Nikoo

Daneshpazhooh

Fahim

et al. 2017

International Journal of Women's Dermatology

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“…Adequate comparison between mucosal and cutaneous LE was proposed a few years ago, 2 and since then, the LE subtypes affecting the lips and oral mucosa have been characterized. [3][4][5] Most aspects of labial compromise in LE are fully discussed in this paper, in contrast to the scarce reports in recent years. [6][7][8] The lip…”

Section: Introductionmentioning

confidence: 95%

“…An important detail may help to differentiate LE from other cheilitis; that is, irrespective of their size or duration, LE lesions usually spread from the vermilion to the skin, blurring the sharp line of the vermilion border. This feature is of diagnostic significance, as it occurs more often than not …”

Section: The Lipmentioning

confidence: 99%

“…Lesions may become dyspigmented, keratotic, eroded, atrophic and verrucous (Figs d and a,b). Labial hypertrophic (verrucous) LE is exceedingly rare; lesions are particularly exuberant and disfiguring (Fig. a,b).…”

Section: Types Of Lupus Erythematosusmentioning

confidence: 99%

“…However, there is much confusion about mucosal LE, with a number of terms in use, including ‘lupus cheilitis’, ‘leucoplakia’, ‘ulcerated plaque’ and ‘chronic plaque’. Adequate comparison between mucosal and cutaneous LE was proposed a few years ago, and since then, the LE subtypes affecting the lips and oral mucosa have been characterized . Most aspects of labial compromise in LE are fully discussed in this paper, in contrast to the scarce reports in recent years …”

Section: Introductionmentioning

confidence: 97%

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The lip in lupus erythematosus

2014

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Lupus erythematosus (LE) frequently compromises the skin, lips and oral mucosa. There is a large body of medical and dental literature about the cutaneous and mucosal lesions of LE, but very little has been written specifically about labial lupus. The lip has a peculiar anatomical and histological architecture, and LE lesions at this site may have some distinct features. This article reviews the existing data and adds some new concepts to the issue of labial lupus in all of its presentations, comparing such lesions to the well-established characterization of cutaneous LE (in acute, subacute and chronic lesions), and highlighting some special clinical features that may enable a better diagnosis and differential diagnosis of lip diseases.

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Dermatoses of the Oral Cavity and Lips

Scully¹

2016

Rook's Textbook of Dermatology, Ninth Edition

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Oral and labial lesions are usually the result of local disease but may be the early signs of systemic disease, including dermatological disorders, and in some instances may cause the main symptoms. This chapter mainly discusses disorders of the periodontal and mucosal tissues that may be related to skin disease and that may present at a dermatology clinic. It should be borne in mind that the professionals most competent in diagnosing and treating oral diseases are those with formal dental training and who are therefore in a position to understand the full complexities of the region. This chapter is divided into a brief discussion of the biology of the mouth, an overview of the more common signs and symptoms affecting specific oral tissues, discussion of the disorders of the oral mucosa of most relevance to dermatology and a tabulated review of oral manifestations of systemic diseases. Only the more classic oral lesions are illustrated. For reasons of space restrictions, diseases affecting the teeth, salivary glands, jaws or temporomandibular joints are not discussed in any depth.

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Hypertrophic (Verrucous) Cutaneous Lupus Erythematosus of the Lip and Oral Cavity: A Series of 4 Cases

Cited by 8 publications

References 10 publications

Persistent lip enlargement: An unusual presentation of lupus erythematosus

Persistent lip enlargement: An unusual presentation of lupus erythematosus

The lip in lupus erythematosus

Dermatoses of the Oral Cavity and Lips

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