Hypertrophic Striae Distensae

Ebert, Michael H.

doi:10.1001/archderm.1933.01460060062011

Cited by 14 publications

(7 citation statements)

References 3 publications

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“…Pinkus, Krech & Mehregan (1966), on the other hand, described numerous thin parallel elastic fibres traversing the entire stria, while the lateral borders showed broken and retracted elastic fibres. This striking parallel arrangement of elastic fibres was also noted by Ebert (1933), but not in all specimens.…”

supporting

confidence: 64%

“…i86 P. Zheng, R.M.Lavker and A.M.Kligman The situation is no better with regard to the histopathology of striae, which always have the same appearance regardless of the cause. They were first studied by Unna in 1894 andGans &Steigleder in 1925, but no consensus has been reached. Contradictory views of their microscopic anatomy have been published by modern authorities.…”

mentioning

confidence: 99%

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Anatomy of striae

1985

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The histopathology of striae distensae is disputed; different authorities give contradictory accounts of the microscopic changes, especially in elastic fibres. We re-evaluated the problem by taking eight elliptical biopsies across striae. Six were examined by light microscopy with appropriate stains for elastin and collagen. Two were prepared for scanning electronmicroscopy (s.e.m.), using a procedure which removes collagen, enabling the elastic network to be seen in its native form. By light microscopy, striae were sharply demarcated from normal skin, consisting mainly of fine, straight bundles of collagen arranged parallel to the surface. Fine elastic fibres were disposed similarly without fragmentation, fraying or curling. By s.e.m., the elastic network was found to be extraordinarily dense and well developed with many fine, curled fibres in random array. It was evident that the routine stains for elastin greatly underestimated the abundance of elastic fibres, probably because immature fibres contain insufficient protein matrix. The horizontal packing of collagen bundles was confirmed by s.e.m. These findings support the view that striae distensae are scars. There is no evidence that they form by stress-induced rupture of the connective tissue.

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confidence: 64%

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confidence: 99%

Anatomy of striae

1985

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“…A complex interaction of genetic, local, and systemic factors that influence healing and immune responses is probably responsible. One theory to account for this is termed locus minoris resistentiae (“sites of reduced resistance to disease”) 27 . This explanation holds that scarred, inflamed, or traumatized skin alters connective tissue and vascular function, thus predisposing it to disease 20,28 .…”

Section: Discussionmentioning

confidence: 99%

“…One theory to account for this is termed locus minoris resistentiae (''sites of reduced resistance to disease''). 27 This explanation holds that scarred, inflamed, or traumatized skin alters connective tissue and vascular function, thus predisposing it to disease. 20,28 Some authors propose that traumatized epithelium may express pemphigus antigens or expose new epitopes, which may initiate antibody formation.…”

Section: Discussionmentioning

confidence: 99%

Pemphigus Foliaceus Masquerading as Postoperative Wound Infection: Report of a Case and Review of the Koebner and Related Phenomenon following Surgical Procedures

Rotunda

BHUPATHY

Dye

et al. 2006

Dermatologic Surgery

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“…Bhangoo et al 5 also observed elastogenesis in scar tissue. Ebert 6 and Breathnach 7 examined striae evolution, from early (striae rubrae) to late (striae albae) phases. Striae rubrae are characterized by inflammation with cuffing of small vessels by lymphocytes and monocytes accompanied by increased mast cells and active fibroblasts, which destroys collagen and elastic fibers.…”

Section: Discussionmentioning

confidence: 99%

Breast Striae After Cosmetic Augmentation

Tsai

Castillo

Moliver

2014

Aesthetic Surgery Journal

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Breast SurgeryBreast augmentation is the most popular cosmetic surgical procedure in the United States; 330 631 procedures were performed in 2012.1 Any complication can be a significant disappointment for the patient and the surgeon. A known but incompletely understood complication of breast augmentation is striae distensae, also called stretch marks.Striae are linear dermal scars that form in areas of dermal damage. The histology is similar to that of scar tissue formation, but the exact origin is still unknown. Investigators have hypothesized that these scars are precipitated by an inflammatory reaction that destroys collagen and elastic fibers, with ensuing regeneration in the direction of the mechanical forces. This results in flattening and atrophy of the epidermis. Many theories have been suggested to explain the etiology of striae formation, including infection, effects of mechanical stretching, hormonal influences, genetic factors, immunosuppressed states, and chronic liver disease. Objectives: The authors investigated their own patient population to discern risk factors for new-onset striae after cosmetic breast augmentation. Methods: A retrospective chart review was performed for patients who underwent primary breast augmentation from 2005 to 2012 in a single-surgeon practice. Initial chart review revealed that only patients aged ≤25 years exhibited new striae; therefore, only patients from this age group were included. Potential risk factors examined included age, body mass index (BMI), oral contraceptive use, time of last menstrual period (LMP), parity, smoking and alcohol status, diabetes mellitus, and personal history of striae. Implant and surgical factors examined included implant material (silicone vs saline), volume, and location (submuscular vs subglandular placement) and the site of incision. Results: Of the 549 patients included in the study, 17 (3.10%) had new-onset striae, observed at a mean of 58 days postoperatively. The risk of striae was statistically significantly higher (P < .05) among patients who were younger (3.3 times), were nulliparous (14.38 times), began their LMP >14 days before surgery (9.24 times), and had a history of striae (6.11 times). There was a strong correlation between new-onset breast striae and implant size, as well as BMI (P = .07). Conclusions: There is a strong correlation between new-onset striae and hormone levels, genetic factors, and tissue stretch components in patients who undergo cosmetic breast augmentation. This information can be utilized to better educate patients about this potential complication. Level of Evidence: 4

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Hypertrophic Striae Distensae

Cited by 14 publications

References 3 publications

Anatomy of striae

Anatomy of striae

Pemphigus Foliaceus Masquerading as Postoperative Wound Infection: Report of a Case and Review of the Koebner and Related Phenomenon following Surgical Procedures

Breast Striae After Cosmetic Augmentation

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