Hypertonic hydroxyethyl starch solution for hypovolaemia correction following heart surgery

Širvinskas, Edmundas; Šneider, Edvin; Švagždienė, Milda; Vaskelyte, Jolanta; Ralienė, Laima; Marchertienė, Irena Agnietė; Adukauskienė, Dalia

doi:10.1177/0267659107078484

Cited by 22 publications

(12 citation statements)

References 28 publications

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“…This is optimized by adjusting the preload, which necessitates an additional adjustment in the infusion therapy. [14] Verheij et al [3] studied the hemodynamic performance of colloid solutions versus crystalloids after cardiac or vascular surgery and discovered that colloid fluid loading increased the cardiac index, but the crystalloids did not have this effect. This difference was attributed to the greater plasma volume expanding effect caused by increased colloid osmotic pressure rather than by the affected cardiac functions.…”

Section: Discussionmentioning

confidence: 99%

An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery

Durukan¹

2013

Turk Gogus Kalp Dama

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Amaç: Bu çalışmada koroner arter baypas cerrahisi yapı-lan hastalarda %6 hidroksietil nişasta 130/0.4'ün etkileri, sıklıkla kullanılan dengeli bir elektrolit solüsyonu ile karşılaştırıldı. Ça lış mapla nı:Koroner arter baypas cerrahisi yapılan 157 hasta iki gruba randomize edildi. İlk gruba %6 hidroksietil nişasta 130/0.4, ikinci gruba ise sıklıkla kullanılmakta olan dengeli bir elektrolit solüsyonu verildi. Her iki solüs-yonun da ameliyat sonrası sonuçlar üzerine olan etkileri araştırıldı. Bul gu lar: Yüze altı hidroksietil nişasta 130/0.4 ameliyat sonrası kan kaybı ve kullanılan kan ve kan ürünü miktarını artırmadı (p>0.05). Renal ve pulmoner fonksiyonlar üzerine olumsuz etkisi saptanmadı. Entübasyon zamanı, yoğun bakım kalış süresi ve ameliyat sonrası hastane kalış süresi açısından gruplar arasında fark görülmedi (p>0.05). Hidroksietil nişastanın ameliyat sonrası atriyal fibrilasyon oluşumu üzerine herhangi bir etkisi saptanmadı (p>0.05). So nuç: Yüze altı hidroksietil nişasta 130/0.4 koroner baypas cerrahisi sonrası sıvı tedavisinde güvenli olarak kullanılabilir.Anah tar söz cük ler: Kalp cerrahisi; kristalloid solüsyonlar; hidroksietil nişasta. Background:This study aims to compare the effects of 6% hydroxyethylstarch 130/0.4 with a commonly used balanced electrolyte solution in patients undergoing coronary artery bypass surgery. Methods: One hundred and fifty seven patients who underwent coronary artery bypass surgery were randomized into two groups. The first group received 6% hydroxyethyl starch 130/0.4, while the second group received a commonly used balanced electrolyte solution. The effects of both solutions on postoperative outcomes were studied. Results: Six percent hydroxyethyl starch 130/0.4 did not increase postoperative blood loss and the amount of blood and blood products (p>0.05). No adverse effect was observed on renal and pulmonary functions. Intubation time, intensive care unit stay and postoperative duration of hospital stay did not differ between the groups (p>0.05). Hydroxyethyl starch had no effect on the occurrence of postoperative atrial fibrillation (p>0.05). Conclusion: Six percent hyroxyethyl starch 130/0.4 may be considered safe in fluid therapy following coronary bypass surgery.

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Section: Discussionmentioning

confidence: 99%

An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery

Durukan¹

2013

Turk Gogus Kalp Dama

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“…In a recent study, the hemodynamic effects of hypertonic colloids (7,2 % HES, HC) was compared with ringer, after CABG (Sirvinskas et al 2007). At 15 min from the infusion, they were shown to significantly increase CI with a lower infused volume.…”

Section: Hypertonic Colloid Solutionsmentioning

confidence: 99%

“…Further similar studies found a negative effect of HES administration on renal function. The need for replacement therapy, correlated to cumulative dose, which was often exceeded (Sirvinskas et al 2007;Ickx et al 2003).…”

Section: Comparison Between Hes and Other Colloidsmentioning

confidence: 99%

Fluid Management and Electrolyte Balance

Vennari

Benedetto

2013

Postoperative Critical Care for Cardiac Surgical Patients

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“…Инфузия 7,2% ГР + ГЭК в ближайшем послеоперацион ном периоде приводила к увеличению диуреза и улучшению респираторной функции легких у больных ишемической бо лезнью сердца после реваскуляризации миокарда [43].…”

Section: о б з о р ыunclassified

Use of Hypertonic Sodium Chloride Solution at Surgery under Extracorporeal Circulation

Ломиворотов¹,

Фоминский²,

Непомнящих³

2012

rmt

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Hypertonic hydroxyethyl starch solution for hypovolaemia correction following heart surgery

Cited by 22 publications

References 28 publications

An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery

An evaluation of 6% hydroxyethyl starch 130/0.4 use in fluid therapy following coronary artery surgery

Fluid Management and Electrolyte Balance

Use of Hypertonic Sodium Chloride Solution at Surgery under Extracorporeal Circulation

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