Hyperthyroidism and Renal Tubular Acidosis

Zisman, Elias

doi:10.1001/archinte.1968.03640020006002

Cited by 14 publications

(2 citation statements)

References 23 publications

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“…To our knowledge, this is the 10th case in which con currence of RTA and thyroid disease has been observed [2,4,5,10,17], Table II summarizes the main features of these 10 patients. It is apparent that in most of these cases the thyroid disease probably had an autoimmune origin, and it is possible though not certain that some of them (i.e., cases 1, 3, and 4) actually had a lymphocytic thy roiditis with spontaneously resolving hyperthyroidism.…”

Section: Discussionmentioning

confidence: 99%

“…It has been noticed, however, that the concurrence of RTA and autoimmune thyroid disease is extremely rare [2,4,5,10,17], Therefore, it has been generally thought that in the latter association, the nature of the link between hyper thyroidism and RTA could be metabolic, via hypercal cemia, hypercalciuria, and nephrocalcinosis, rather than immunological [2,4,5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Distal Renal Tubular Acidosis and Lymphocytic Thyroiditis with Spontaneously Resolving Hyperthyroidism

Jaeger¹,

Portmann²,

Wauters³

et al. 1985

Am J Nephrol

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In a 3 3-year-old woman concurrence of a complete distal renal tubular acidosis (RTA) and lymphocytic thyroiditis with spontaneously resolving hyperthyroidism was observed. Until recently, the rare association of RTA and hyperthyroidism had been thought to be governed by nephrocalcinosis, via hypercalcemia and hypercalciuria. However, in this case, nephrocalcinosis was not present, but there were histological signs of renal interstitial mononuclear cell infiltration, and the RTA persisted despite the resolution of the hyperthyroidism. This observation supports the idea that immunological mechanisms may relate RTA and hyperthyroidism when the latter has an autoimmune origin.

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Section: Discussionmentioning

confidence: 99%