Hypertension and arrhythmia: blood pressure control and beyond

Yildirir, Aylin; Batur, Mustafa Kemal; Oto, Ali̇

doi:10.1053/eupc.2002.0227

Cited by 37 publications

(37 citation statements)

References 75 publications

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“…Ventricular tachycardia can be found in 7-18% [26]. Some authors [24] found that concentric hypertrophy carries the greatest risk, and the eccentric a moderate risk of death and of CV complications. Nunez et al [6] found equal prevalence and complexity of ventricular arrhythmias in hypertensive patients with concentric and asymmetric LVH.…”

Section: Discussionmentioning

confidence: 99%

“…The probability is that only explicitly abnormal values (i.e., those >100 ms) outside error margins may potentially have a practical value, suggesting a markedly abnormal repolarisation [23]. Scarce data was published regarding QTc interval prolongation/QTd and complex ventricular arrhythmias in hypertensive patients with LVH [24,25], but which type of LVH has the greatest influence has been understudied (especially for the asymmetric type).…”

Section: Qt Interval and Qt Dispersionmentioning

confidence: 99%

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Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias

Kunišek¹

2012

Cardiac Arrhythmias - New Considerations

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Section: Discussionmentioning

confidence: 99%

Section: Qt Interval and Qt Dispersionmentioning

confidence: 99%

Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias

Kunišek¹

2012

Cardiac Arrhythmias - New Considerations

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“…Besides, there was an increased incidence of impairment of left ventricular diastolic filling and left atrial enlargement [8]. The development of left ventricular hypertrophy in hypertensive patients appears to be the main link between hypertension and ventricular arrhythmias, as patients with left ventricular hypertrophy are more likely to develop ventricular arrhythmias than the hypertensive population without [56][57][58].…”

Section: Cardiac Arrhythmiasmentioning

confidence: 95%

“…It is particularly of great importance for cardiac surgeons and physicians from other specialties to be acknowledged of what and how cardiac surgical issues may develop associated with hypertension and may eventually warrant a surgical intervention. As a result, several conditions, such as coronary artery disease [3], acute aortic syndrome [4], congenital [5,6] and valvular heart disease [7], and arrhythmias [8] can be involved. The role that hypertension plays in these conditions can be complex, including hemodynamic, electrophysiological and biomolecular factors.…”

Section: Introductionmentioning

confidence: 99%

Cardiac surgery and hypertension: a dangerous association that must be well known

Yuan¹,

Hua²

2011

Rev Bras Cir Cardiovasc

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It is well-known that hypertension is a very common disease, and severe cerebrovascular accidents might occur if the blood pressure is not properly controlled. However, conditions associated with uncontrolled hypertension may be overlooked, and may become critical and eventually require a surgical intervention on an urgent basis. Coronary artery disease, acute aortic syndrome, congenital and valvular heart disease, and arrhythmias are under this topic of discussion. Of them, coronary artery disease including myocardial infarction and especially postinfarction myocardial rupture, and aortic dissection are major critical situations that physicians may encounter in clinical practice. The role that hypertension plays in these conditions can be complex, including hemodynamic, electrophysiological and biomolecular factors, where the latter may prevail in the current era. Coronary artery disease may be associated with a reduced nitric oxide synthesis. Transforming growth factor and matrix metalloproteinases have been observed in relation to aortic syndrome. Wnt, p38 and JNK signaling pathway may be involved in the development of ventricular hypertrophy responsible for cardiac arrythmias. Various gene phynotypes may present in different congenital heart defects. This article is to present these conditions, and to Cardiac surgery and hypertension: a dangerous association that must be well knownCirurgia cardíaca e hipertensão: uma associação perigosa que deve ser bem conhecida Resumo É sabido que a hipertensão é uma doença muito comum, e que os acidentes cerebrovasculares graves podem ocorrer se a pressão sanguínea não for apropriadamente controlada. Contudo, as condições associadas à hipertensão não controlada podem ser negligenciadas, e tornarem-se críticas, necessitando, eventualmente, uma intervenção cirúrgica urgente. Doença coronariana, síndrome aórtica aguda, cardiopatias congênitas, valvopatias e arritmias são sob este tópico de discussão. Dentre eles, a doença corornariana, inclusive o infarto do miocárdio e especialmente a ruptura cardíaca pós-infarto e a dissecção aórtica, são as situações críticas principais que os médicos podem encontrar na prática clínica. O papel que a hipertensão desempenha nessas condições pode ser complexo, incluindo fatores further discuss the possible etiologies and the potential treatment strategies so as to highlight the relevance at a prognostic level.Descriptors: Cardiac Surgical Procedures. Heart Diseases. Hypertension. YUAN, SM & JING, H -Cardiac surgery and hypertension: a dangerous association that must be well knownRev Bras Cir Cardiovasc 2011;26(2):273-81 vascular tissue associated with increased endocrine and local paracrine effects; 2) the impact of the common risk factors, such as high blood pressure, that exaggerate and accelerate atherosclerotic process; and 3) hemodynamic factors, which may destabilize vascular lesions and precipitate acute events [3].A modest short-term reduction in blood pressure confers a reduction in coronary artery disease events of abou...

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“…Even in the case of the two patients with abnormal LPs, one can argue that the abnormal LPs resulted from other cardiovascular noxious factors such as hypertension, dyslipidemia, old myocardial infarction, or aortic stenosis, all of which are known to be associated with abnormal LPs (30)(31)(32). This suggests that FMF amyloidosis, even after long duration (seven patients had already undergone kidney replacement therapy), may spare the heart and that inflammation in FMF, with a severe enough degree to cause systemic amyloidosis, may not The late potential test was considered abnormal when two of the following criteria were met: 1) fQRS > 114 ms; 2) RMS40 < 20 μV; and 3) LAS >38 ms be sufficiently atherogenic to cause aberrant ventricular conduction.…”

Section: Discussionmentioning

confidence: 99%

Late ventricular potentials in familial Mediterranean fever with and without AA amyloidosis

Nussinovitch¹,

Livneh²

2017

Eur J Rheumatol

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Data on increased rhythm and conduction disturbances in FMF are limited and conflicting. For instance, Akcay et al. (13) found that QT dispersion (QTd) and corrected dispersion (QTcd), which reflect cardiac repolarization heterogeneity and thereby suggest predisposition for cardiac arrhythmias, are increased in uncomplicated FMF. However, different methodologies have yielded normal QTd results in both uncomplicated and amyloidosis-affected FMF patients (14, 15). Limited information is found on depolarization-associated markers for arrhythmias. Low-amplitude, high-frequency waves-termed late ventricular potentials (LPs)-can be detected immediately adjacent to the QRS complex by signal-averaged electrocardiography Udi Nussinovitch 1 , Avi Livneh 2,3Original Article Abstract Objective: Familial Mediterranean fever (FMF) is an autosomal recessive disease characterized by episodic and chronic inflammation that may lead to both accelerated coronary atherosclerosis and cardiac AA amyloidosis. We hypothesized that late ventricular potentials (LPs), an established electrocardiographic susceptibility marker of ventricular arrhythmias, will be more common in FMF than in the adjusted normal population due to these two types of inflammation-associated cardiac effects. Therefore, we aimed to evaluate the occurrence of LPs in FMF patients with and without amyloidosis.Material and Methods: Signal-averaged electrocardiography was performed in consecutive patients with FMF using the Frank corrected orthogonal lead system. At least 200 consecutive beats were digitally recorded and averaged, and the presence of LPs was determined according to acceptable thresholds.Results: There were 54 patients with colchicine-treated FMF, of whom 14 had biopsy-proven AA amyloidosis. None of the uncomplicated FMF patients and 2 of the 14 FMF amyloidosis patients had abnormal or borderline LPs. Conclusion:Based on LPs as a susceptibility marker for arrhythmia, FMF patients, including the large majority of FMF patients with amyloidosis, are seemingly not at an increased risk to develop arrhythmias.

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Hypertension and arrhythmia: blood pressure control and beyond

Cited by 37 publications

References 75 publications

Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias

Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias

Cardiac surgery and hypertension: a dangerous association that must be well known

Late ventricular potentials in familial Mediterranean fever with and without AA amyloidosis

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