Hypertension: a cause of growth impairment

Deshpande, P V; Gilbert, R. D.; Williams, J. David; Hulton, SA; Milford, DV

doi:10.1038/sj.jhh.1001389

Cited by 5 publications

(2 citation statements)

References 8 publications

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“…Therefore, our data do not allow to state which phenomenon is the cause and which is the effect. Moreover, selected cases of growth impairment in children (1-7 years) due to severe (DBP > 100 mm Hg) hypertension were published, and control of hypertension resulted in improved growth [24]. Curiously, some data gathered on our human adolescents remember previous data described by Rodriguez-Padilla et al [25] on rats, i.e., body weight is higher in hypertensive rats vs. controls.…”

Section: Discussionsupporting

confidence: 65%

Adolescence as possible critical temporal window for blood pressure short term monitoring in boys and girls

et al. 2005

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Adolescence is a critical temporal window for the development of obesity in adult age. We studied this period for short-term monitoring of blood pressure in both genders. Weight, height, body mass index (BMI), systolic and diastolic blood pressure (SBP, DBP) were recorded in 937 adolescents, 474 boys and 463 girls aged 12 years, and again 2 years later in the same subjects. Boys with BP values > or = 95th percentile at both ages (no. = 8) showed at 12 years weight (kg 61.4) height (cm 159.5) and BMI (23.5), and also at 14 years (77.0, 172.4, 25.6) values consistently higher than boys with high BP values at either ages taken singularly (no. = 32 + 32) (mean 49.2, 154.4, 21.5, respectively, at 12 years, and 62.1, 167.0, 22.2 at 14 years). These 64 boys, had values higher than boys with BP always below the 95th percentile (no. = 402) (45.5, 151.4, 19.7 at 12 years, and 56.9, 164.6, 20.9 at 14 years). This was confirmed for weight and BMI in girls. Stepwise logistic regression revealed that weight at 12 years and high BP values at 12 years were predictive independent risk factors for hypertension at 14 years. Odds ratio indicated that increment of body weight unit (1 kg) at 12 years predicted an average increase of 4% of risk for high BP values at 14 years, while high BP values at 12 years was predictive for a 2.19 times risk for high BP values at 14 years. Body weight, BMI and BP at 12 years of age may give useful indications for the prevision (and possible prevention) of hypertension and overweight at 14 years of age.

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Section: Discussionsupporting

confidence: 65%

Adolescence as possible critical temporal window for blood pressure short term monitoring in boys and girls

et al. 2005

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“…RVH has been described as a rare cause of FTT, and probably occurred in this case, since growth recovery occurred after improvement of BP levels 5 10 11…”

Section: Discussionmentioning

confidence: 80%

Renovascular hypertension: a case with atypical neurological signs

Jerónimo¹,

Dionísio²,

Gomes³

et al. 2015

BMJ Case Reports

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SUMMARYSecondary hypertension is the most frequent form of hypertension in children. Renovascular disease accounts for 5-10% of all childhood hypertension and should be suspected in the presence of severe hypertension found difficult to manage with medical therapy. Uncontrolled hypertension can lead to severe target organ damage. We describe the case of a 13-month-old baby boy with failure to thrive, recent muscular weakness of the lower extremities and irritability. Hypertension was detected and he was admitted to the paediatric intensive care unit with a refractory hypertensive emergency, despite multiple antihypertensive therapies. Bilateral renal artery stenosis was diagnosed through renal angiography and balloon dilation was performed, leading to lower blood pressure. He is currently withdrawing from antihypertensive medication, and slowly gaining weight and recovering from target organ damage. However, weakness of the lower extremities persists and he has been diagnosed with a neurogenic bladder. BACKGROUND

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Systemic Hypertension

Sinha¹,

Reid²

2010

Paediatric Cardiology

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Hypertension: a cause of growth impairment

Cited by 5 publications

References 8 publications

Adolescence as possible critical temporal window for blood pressure short term monitoring in boys and girls

Adolescence as possible critical temporal window for blood pressure short term monitoring in boys and girls

Renovascular hypertension: a case with atypical neurological signs

Systemic Hypertension

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