Hypersensitivity to proton pump inhibitors: Lansoprazole-induced Kounis syndrome

Recurrent acute myocardial infarction and Kounis syndrome

“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14] We present a case of recurrent acute myocardial infarction associated with an allergic reaction in an 83-year-old Italian woman. On July 1, 2008, an 83-year-old Italian woman was admitted to the emergency department with chest pain.…”

Kounis Syndrome secondary to cefuroxime axetil use in an asthmatic patient

“…Main pathophysiological mechanism is vasospasm of epicardial coronary arteries due to increased inflammatory mediators that are released during a hypersensitivity reaction [1]. The trigger may be drugs [2][3][4][5][6][7], chemicals [9], foreign bodies [10][11][12][13][14], environmental exposures [8,[24][25][26][27][28] or some other conditions that give rise to inflammatory mediator release [15]. Anaphylactic or anaphylactoid reactions can make clinical situation even more serious.…”

Kounis syndrome in a patient with ovarian cancer and allergy to iodinated contrast media: Report of a case

“…On the other hand Kounis syndrome has also been associated with tako-tsubo syndrome [15,16] and with many other anecdotical clinical conditions such as viper bite or hymenoptera sting [17][18][19][20], administration of some drugs like penicillin [4,21], amoxicillin [22], diclofenac sodium [23], rocuronium [24], mesalamine [25], proton pump inhibitors like lansoprazole [26], and even aspirin [27].…”