Hyperostosis Frontalis Interna

Frontal cortex dysfunction due to extensive hyperostosis frontalis interna

“…Sexual hormones for example, oestrogen stimulation,1–could play a part in the emergence of HFI and explain its predominance among female. Other metabolic disorders or endocrinopathies have been highlighted, such as acromegaly (especially when associated with hyperprolactinemia),10 11 diabetes or leptin hyper secretion 8 12. Genetic predisposing factors are also involved 6 13…”

The clinical manifestations of hyperostosis frontalis interna: A qualitative systematic review of cases

“…Vision dysfunctions were found in 10 patients (Feiring & Davidoff, 1947;Harding, 1949;Khansare, 2014;Lieberman & Ferry, 1974;Sacher et al, 1985;Suárez Alvarez et al, 2004); Diabetes was found in 10 patients (Andrews, 1942;She & Szakacs, 2004;Sommers, 1953;Suárez Alvarez et al, 2004;Talarico et al, 2008;Torrealba-Acosta & Mandel, 2020); Hypertension was found in 8 patients (Devriendt et al, 2005;Moore & Carr, 1952;She & Szakacs, 2004;Sommers, 1953;Suárez Alvarez et al, 2004;Talarico et al, 2008;Waclawik, 2006;Wanski et al, 1979); History of head trauma was found in 4 patients (Elghazouani, 2021;Li et al, 2017;Talarico et al, 2008;Willison et al, 1993); Energy decrease/fatigue were found in 3 patients (Bracanovic et al, 2020;Willison et al, 1993;Yamakawa et al, 2006); Frontal lobe compression was found in 3 (de Zubicaray et al, 1997;Hasegawa et al, 1983;Nakanishi et al, 1990); Cerebral atrophy was found in 3 patients (Devriendt et al, 2005;Elghazouani, 2021;Talarico et al, 2008); Epilepsy was found in 2 patients (CARR, 1936;Winant et al, 2013); Cystic ovaries was found in 1 patient (Sommers, 1953); Endocrine dysfunctions were further categorized by specific diagnosis, thyroid hypertrophy + ad...…”

“…The symptoms, diseases, and disorders of each patient with HFI were extracted individually. These conditions are listed in descending order of prevalence within the studies: Headaches were found in 51 patients (Elliott, et al, 2014; Andrews, 1942; Bracanovic et al, 2020; CARR, 1936; Chen & Murthy, 2012; Dann, 1951; Dumas et al, 1994; Harding, 1949; Khansare, 2014; Li et al, 2017; Lieberman & Ferry, 1974; Moore & Carr, 1952; NOTKIN, J., 1953; Priyambada et al, 2017; Ramchandren & Liebeskind, 2007; Sacher et al, 1985; Schmitt, 1976; Suárez Alvarez et al, 2004; Talarico et al, 2008; Willison et al, 1993; Yang et al, 2018); Obesity was found in 36 patients (Devriendt et al, 2005; Harding, 1949; She & Szakacs, 2004; Sommers, 1953; Torrealba‐Acosta & Mandel, 2020); Vertigo/Dizziness symptoms were found in 33 patients (Harding, 1949; Hasegawa et al, 1983; Moore & Carr, 1952; NOTKIN, J., 1953; Prakash et al, 2011; Talarico et al, 2008); Cognitive decline/Memory loss/Dementia were found in 30 patients (CARR, 1936; de Zubicaray et al, 1997; Devriendt et al, 2005; Gilbert et al, 2012; Khansare, 2014; Li et al, 2017; NOTKIN, J., 1953; Priyambada et al, 2017; Sacher et al, 1985; Waclawik, 2006); Psychological diagnosis were further categorized by specific diagnosis, depression was found in 27 patients (Harding, 1949; Khansare, 2014; NOTKIN, J., 1953; Otter et al, 2012; Smith & Hemphill, 1956; Torrealba‐Acosta & Mandel, 2020), unspecified psychological disorders were found in 17 patients (Devriendt et al, 2005; NOTKIN, J., 1953; Schmitt,…”

Failing Vision Caused by a Bony Spike Compressing the Optic Nerve within the Optic Canal : Report of Two Cases Associated with Morgagni's Syndrome Benefited by Operation

“…incidence of visual symptoms, but did not amplify this statement. Since then several other`authors have recorded in passing an occasional case with visual failure (Eisen, 1936;Andrews, 1942). 279 …”