Hyperkinetic borderline hypertension in Tecumseh, Michigan

Julius, Stevo; Krause, Lisa; Schork, Nicholas J.; Mejia, Agnes D.; Jones, Kerin A.; Ven, Cosmas van de; Johnson, Ernest H.; Sekkarie, Mohamed; Kjeldsen, Sverre E.; Petrin, Jurij; Schmouder, Robert; Gupta, Rakesh; Ferraro, James C; Nazzaro, Pietro; Weissfeld, Joel L.

doi:10.1097/00004872-199101000-00012

Cited by 238 publications

(82 citation statements)

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“…A study in Preston in women and men with low birth weight showed that there is a relationship with a resting pulse rate of the highest [113]. This is consistent with the hypothesis that a sympathetic activity is established in the uterus in the child with retarded growth and leads to an increase in blood pressure in the adult life [60] but the swelling can equally affect both systems.…”

Section: Nervous Systemsupporting

confidence: 77%

Eugenic Therapy and the Metabolic Syndrome

Quintero¹

2017

Epidemiology

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SummaryIndependent of the clinical syndrome that results in chronic inflammation, there is an overlap of the different etiopathogenic factors in the most common diseases of the modern era. Its pathogenesis also has similar pathophysiological mechanisms. Independent of the clinical syndrome that results in chronic inflammation, there is an overlap of the different etiopathogenic factors in the most common diseases of the modern era. Its pathogenesis also has similar pathophysiological mechanisms. These two facts prompt us, independent of the particular therapeutic connotations for each disease, to establish certain measures of prevention and treatment, also common, where precisely the holistic treatments that seek to Systemic homeostasis, are appropriate. These are the biological treatments, where the homo-toxicology, without a doubt, stands out as one of the best therapeutic alternatives.The universal concept of inflammation allows us to understand more than just the symptom and going beyond a therapeutic protocol, unfortunately a lasting solution is not in our hands and may be the anthropology, sociology and ecology, the sciences involved in the definitive solutions. In the meantime, to understand that the chronic disease of the adult may have originated during gestation or before the same. We have to look at humanity in full, in its family nucleus, interacting with an environment, in a dynamic process, involutionary and evolutionary at the same time, but it will be the knowledge of our own nature which will allow a better pathogenetic and therapeutic approach.At the end of the first millennium and the start of the second a new profile in sicknesses made itself evident and it would be naive as to think that there was no epidemic relationships between the illnesses that made them up. In today's society, the analysis of each individual sickness, without taking into account the biological changes surrounding the environment in the development of modern day life, would isolate man as a strange object in his own universe and perpetuate the reductionist concept of the Cartesian medicine where the dismembering of the human body in its sickness makes an important part of its philosophy. Under the integration prism of the environmental conditions we shall analyse the epidemic variants in the prevailing illnesses. And in one medical concept we will integrate the environmental changes with the psycho, neuro, endocrine and immunological alterations of the organism, which is the origin of almost all human disease.Keeping in mind the environmental conditions for thousands of years in the life development were relatively stable. Evolution made a permanent adjustment that allows the successful existence of life on the planet. Unfortunately, in the last few decades, human life and its relation with the stability of nature around it have changed in such a violent and extreme manner that the human being, from the biological point of view, is not prepared to defend and prosses the information which an adverse environment supplies ...

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Section: Nervous Systemsupporting

confidence: 77%

Eugenic Therapy and the Metabolic Syndrome

Quintero¹

2017

Epidemiology

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“…In the present study, heart rate was increased in subjects with obesity. A high heart rate often accompanied by hypertension in the young is a marker of increased sympathetic nervous system activity 19) , which is related to insulin resistance and/or obesity 20,21) . We have previously reported that increased levels of insulin and leptin in obesity were associated with a high heart rate 7) .…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Metabolic Syndrome in Young Men in Japan

Saito

Mori

Shibata

et al. 2007

JAT

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. Of the 1446 students (mean age 15 years), 96 (6.6%) were obese and 158 (10.9%) were mildly obese. Results: The overall prevalence of metabolic syndrome was 1.4%, being present in; 15.6% of obese subjects. Overall, elevated systolic BP was most common (19.9%). In obese subjects, 51% had an elevated systolic BP. Conclusion: Our study suggests that metabolic syndrome is present in more than 1% of male adolescents and 15% of obese male adolescents in Japan.

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“…Higher heart rate is a predictor of cardiovascular mortality (18)(19)(20)(21)(22)(23)(24), is a strong marker of increased sympathetic tonus (25,26), which can cause insulin resistance (27), and affects all other risk factors (28). Higher heart rate has also been associated with cardiovascular risk factors and the clustering of risk factors (29).…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular Risk Factors Associated with Pulse Pressure in a Screened Cohort in Okinawa, Japan.

et al. 2003

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We evaluated the association between pulse pressure (PP) and cardiovascular risk factors in a screened cohort. Individuals who were receiving medications for hypertension or heart disease, who had no ECG record, or who had a record of arrhythmia were excluded. In total, 8,508 subjects (5,299 men and 3,209 women; age range, 18 to 89 years) were studied. Subjects were divided into four PP classes: PP.1 (PP 40 mmHg, n 2,127), PP.2 (40 PP 44 mmHg, n 2,127), PP.3 (44 PP 50 mmHg, n 2,127) and PP.4 (50 mmHg PP, n 2,127). Multiple regression analysis was used for evaluating the association between PP and cardiovascular risk factor or lifestyle. In men, the regression coefficient was 0.27 for age, 2.50 for diabetes mellitus, 0.33 for uric acid, 0.20 for body mass index, 0.07 for heart rate, 0.83 for current smoking habit and 1.23 for habitual drinking. In women, the regression coefficient was 0.37 for age, 4.09 for diabetes mellitus, 0.42 for body mass index, 0.14 for heart rate, and 0.84 for habitual exercise. In both men and women, PP was significantly increased in association with an increase in the number of risk factors (diabetes mellitus, obesity, current drinking status, heart rate, and hyperuricemia). In conclusion, higher PP was associated with cardiovascular risk factors. These associations were similar in both men and women. older subjects, is an independent predictor of coronary heart disease (3-7). In their prospective population-based study, the Framingham group found that cardiovascular mortality, and particularly coronary mortality, was independently related with initial SBP, DBP, and PP, and that PP showed the strongest association (8). Therefore, the goal of the present study was to evaluate the association of PP with classical cardiovascular risk factors in a screened cohort in Okinawa, Japan.

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Hyperkinetic borderline hypertension in Tecumseh, Michigan

Cited by 238 publications

References 0 publications

Eugenic Therapy and the Metabolic Syndrome

Eugenic Therapy and the Metabolic Syndrome

Prevalence of Metabolic Syndrome in Young Men in Japan

Cardiovascular Risk Factors Associated with Pulse Pressure in a Screened Cohort in Okinawa, Japan.

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