Hyperkeratotic varicella zoster virus infection in an HIV-infected patient. Successful treatment of persistent lesions with cryosurgery

Schöfer, Helmut; Baur, Susan; Gregel, Carola; Wolter, M.; Milbradt, R

doi:10.1046/j.1365-2133.1998.02200.x

Cited by 7 publications

(4 citation statements)

References 6 publications

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“…46,95,108,116 Cryosurgery is another solution for wart-like persistent VZV lesions. 84 Treatment with oral thalidomide (100 mg, 2 3/d) was shown to be successful after only 1 week in an HIV-infected, HAART-receiving patient with VCV as well as cidofovir-and foscarnet-resistant CHSV. 105 Thalidomide probably acts by immune-enhancing mechanisms, but others have reported treatment failure.…”

Section: Pathogenic Mechanismsmentioning

confidence: 99%

Chronic mucocutaneous herpes simplex virus and varicella zoster virus infections

Wauters¹,

Lebas²,

Nikkels³

2012

Journal of the American Academy of Dermatology

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Section: Pathogenic Mechanismsmentioning

confidence: 99%

Chronic mucocutaneous herpes simplex virus and varicella zoster virus infections

Wauters¹,

Lebas²,

Nikkels³

2012

Journal of the American Academy of Dermatology

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“…The successful use of cryosurgery for acyclovir‐resistant varicella zoster virus infection in an HIV‐positive patient has been reported. 31 Ten to 15 s freezes of typical lesions were performed every 2 weeks and a complete remission was achieved after 3 months.…”

Section: Range Of Treatable Benign Lesionsmentioning

confidence: 99%

Cryosurgery of benign skin lesions

Thai

Sinclair

1999

Aust J Dermatology

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Cryosurgery is a widely used treatment modality in dermatology. Its place in cutaneous malignant and premalignant disease is well established; however, it also has great utility with benign lesions. Vascular, infectious, fibrotic diseases, solar damage, acne, as well as some cosmetic defects are amenable to freezing. The mechanism of treatment involves inducing tissue damage, vascular stasis and occlusion, as well as inflammation, to destroy unwanted tissue. After destruction of epidermal lesions, healing involves rapid re-epithelialization over a relatively cold-insensitive dermal network. Side effects are common but shortlived and are rarely severe. The equipment required is relatively economical and readily available. The technique is straightforward and reproducible, making cryosurgery an attractive option for many commonly encountered benign skin conditions. This review outlines treatment with the timed spot freeze technique of some commonly encountered benign lesions.

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“…Most herpes zoster cases in HIV infected patients show common clinical features, e.g., segmental distribution of herpetiform vesicles. Atypical courses like multi‐segmental or generalized distribution, ecthymatous, pox‐like ulcerations, and persistent and hyperkeratotic/verrucous lesions have been described 3–8 …”

mentioning

confidence: 99%