Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis

Falciglia, Mercedes

doi:10.1097/ccm.0b013e3181d8be4b

Cited by 2 publications

(1 citation statement)

References 50 publications

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“…Type 2 diabetes can be defined as an impaired utilization or insufficient amount of insulin that is produced by the pancreas which progresses slowly over time. Uncontrolled diabetes in majority of hospitalized patients is associated with increased risk of morbidity and mortality, increased the length of hospital stay and re-hospitalization rate [4] [5] [6].…”

Section: Introductionmentioning

confidence: 99%

Clinical Outcomes Associated with Use of Subcutaneous Sliding Scale Insulin Compared to Other Insulin Regimens in Hospitalized Patients

Alfehaid¹,

Alotaibi²,

Alanazi³

et al. 2018

IJCM

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Background: Hyperglycemia in hospitalized patients is managed through one of the following approaches: sliding scale insulin (SSI) alone; SSI plus long-acting insulin and basal-bolus insulin (BBI). The optimal insulin treatment regimen is still debated. Objectives: To evaluate the clinical outcomes associated with the use of SSI compared to other regimens. Setting: The general medical wards in King Abdulaziz Medical City, Riyadh, Saudi Arabia.Methods: Medical charts for adult patients admitted between October 2014-December 2015 with type 2 diabetes or uncontrolled hyperglycemia with insulin treatment were reviewed. Data from capillary blood glucose were measured daily for the first 5 days of hospitalization and recorded. Demographics and blood glucose levels were compared by group using one-way ANOVA or Chi-square test. The number of hyperglycemic/hypoglycemic episodes was analyzed using the Kruskal-Wallis test. Results: A total of 240 patients were included. The three insulin regimen groups were not statistically different in terms of the number of days with episodes of hyper-or hypoglycemia (p > 0.05). However, a significantly bigger change from baseline (improvement) in random blood glucose (RBG) levels was observed in BBI and SSI plus glargine patients compared to SSI (p = 0.014). Conclusion: Our study showed no significant difference in the number of days with episodes of hyper-or hypoglycemia for SSI vs. other insulin regimens. However, SSI patients had less improvement in their RBG levels compared to other insulin regimen groups. Further studies with a larger sample size are needed to confirm these findings.

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Section: Introductionmentioning

confidence: 99%

Clinical Outcomes Associated with Use of Subcutaneous Sliding Scale Insulin Compared to Other Insulin Regimens in Hospitalized Patients

Alfehaid¹,

Alotaibi²,

Alanazi³

et al. 2018

IJCM

View full text Add to dashboard Cite

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Sensory nerve conduction study of median ulnar and radial nerves in type 2 diabetic individuals in the age group 40–80 years

Sepat

Wasnik

2020

Heliyon

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Aim The study intends to find out the effect of Type 2 diabetes on the sensory nerve of the upper extremity. Method This research includes 100 subjects, both male and female, within the age group of 40–80 years. The subjects were divided into two groups, A and B. Where Group A includes 50 subjects which diagnosed type 2 diabetic mellitus. Furthermore, Group B holds 50 normal healthy subjects investigated and normal healthy subjects without diabetes mellitus . Written consent was obtained from the subjects who were ready to be part of this study. Orthodromic sensory nerve conduction studies of median, ulnar, and radial nerve were assessed by using EMG diagnostic device for bilateral upper extremities in both groups. The sensory nerve conduction study included nerve conduction velocity (m/s), latency (ms), and amplitude (μV). The data analyzed using paired 't' test within the group and unpaired 't' test between two groups, using computational statistical software Graph Pad Prism. 'p' value < 0.05 was considered to be statistically significant. Results The sensory nerve amplitude of all three nerves reduced the velocity of the median & ulnar nerve was reduced and prolonged latency of ulnar nerve in type 2 diabetics as compared to the Non-diabetics group. Conclusion This study concluded that the type 2 diabetics group has severe sensory nerve affections of the median and ulnar nerve. The therapist should examine the upper extremity of all diabetic subjects, and hand care should be taught to the patients to prevent further complications of diabetic peripheral neuropathy.

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Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis

Cited by 2 publications

References 50 publications

Clinical Outcomes Associated with Use of Subcutaneous Sliding Scale Insulin Compared to Other Insulin Regimens in Hospitalized Patients

Clinical Outcomes Associated with Use of Subcutaneous Sliding Scale Insulin Compared to Other Insulin Regimens in Hospitalized Patients

Sensory nerve conduction study of median ulnar and radial nerves in type 2 diabetic individuals in the age group 40–80 years

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