Hyperglycemia as a prognosis predictor of length of stay and functional outcomes in patients with acute ischemic stroke

Abstract

Hyperglycemia is a prognosis predictor of LOS and functional outcomes of patients with acute ischemic stroke measured by discharge Barthel index.

Prevalence of diabetes and its effects on stroke outcomes: A meta‐analysis and literature review

“…Geographically, the mean prevalence of diabetes in stroke inpatients was highest in Southeast Asian (Singapore, India, Indonesia) and East Asian countries (China, Japan, Taiwan), which were 33.5 and 32.3%, respectively, and mostly in Taiwan. The mean prevalence in studies from North America and Europe was 27.5 and 26.4%, respectively.…”

“…Stress hyperglycemia has been associated with poorer functional outcomes and mortality, irrespective of diabetes status after an acute ischemic stroke. However, more studies have found that stress hyperglycemia has been associated with infarct volume growth, early neurological deterioration (increase of ≥4 points on National Institute of Health Stroke Scale), poorer functional outcome, higher mortality and longer hospital stay in people without a history of diabetes, including patients who underwent thrombolysis and mechanical thrombectomy. This association remained even after adjusting for stroke severity and stroke subtype.…”

“…In a majority of the studies included in the present review, an admission random glucose or a FBG was carried out and included in the analysis of the outcomes. Stress hyperglycemia has been associated with poorer functional outcomes 15,17,40,70 and mortality 71 , irrespective of diabetes status after an acute ischemic stroke. However, more studies have found that stress hyperglycemia has been associated with infarct volume growth, early neurological deterioration (increase of ≥4 points on National Institute of Health Stroke Scale) 16 , poorer functional outcome 12,40,41,71,72 , higher mortality 32,43,46,53,73 and longer hospital stay 40 in people without a history of diabetes, including patients who underwent thrombolysis 71,[74][75][76] and mechanical thrombectomy 77 .…”

“…, India 32 , Indonesia40 ) and East Asian countries (China8,29,38,41 , Japan 16,26 , Taiwan 11,42-44 ), which were 33.5 and 32.3%, respectively, and mostly in Taiwan11,43,44 . The mean prevalence in studies from North America12,13,20,21,30,37,[45][46][47] and Europe 5,7,17,34-36,48-53 was 27.5 and 26.4%, respectively.…”

Safe and Quick Control of Hyperglycemia with Luseogliflozin in Case of High-Dose Intensive Insulin User in an Acute Ischemic Stroke Stage: A Case Report

“…Type 2 diabetes mellitus (DM) is one of major risk factors of stroke and hyperglycemia at the time of acute ischemic stroke increases the risk of hemorrhagic transformation with iv-TPA treatment and it is associated with poor clinical outcomes, longer inhospital stay, increased cost, and mortality [1][2][3][4][5][6]. However, it hasn't been established how to manage hyperglycemia safely in an acute stroke stage, particularly in cases of high-dose insulin users.…”