2019
DOI: 10.1016/j.jpeds.2019.02.027
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Hyperglycemia and Glucose Variability Are Associated with Worse Brain Function and Seizures in Neonatal Encephalopathy: A Prospective Cohort Study

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Cited by 55 publications
(32 citation statements)
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“…Em outra coorte, realizada por Pinchefsky et al (2019), verificou a incidência de 29% de hipoglicemia e 36% de hiperglicemia entre os neonatos com EHI submetidos à HT, quando indicada. A hiperglicemia, mas não a hipoglicemia, foi associada a pior função cerebral global, maior frequência de convulsões no monitoramento de eletroencefalograma de amplitude integrada (aEEG) e pior pontuação no ciclo sono-vigília.…”
Section: Resultsunclassified
“…Em outra coorte, realizada por Pinchefsky et al (2019), verificou a incidência de 29% de hipoglicemia e 36% de hiperglicemia entre os neonatos com EHI submetidos à HT, quando indicada. A hiperglicemia, mas não a hipoglicemia, foi associada a pior função cerebral global, maior frequência de convulsões no monitoramento de eletroencefalograma de amplitude integrada (aEEG) e pior pontuação no ciclo sono-vigília.…”
Section: Resultsunclassified
“…Bei Neugeborenen mit HIE ist ein frühes pathologisches Blutzuckerprofil (d. h. Hypoglykämien, Hyperglykämien oder schwankende Blutzuckerwerte) im Vergleich zur Normoglykämie mit deutlichen Mustern von zerebralen Schädigungen im MRT assoziiert [ 325 ]. Hyperglykämien und schwankende Blutzuckerwerte waren im amplitudenintegrierten EEG zudem mit einer pathologischen globalen Gehirnfunktion und Krampfanfällen assoziiert [ 336 ].…”
Section: Wissenschaftliche Grundlagen Auf Deren Basis Die Empfehlungeunclassified
“…In newborns, both hypoglycemia and hyperglycemia increase the risk of brain injury and poor neurological prognosis. [195][196][197][198][199][200][201] Therefore, blood glucose levels should be monitored immediately after resuscitation, and both hypoglycemia and hyperglycemia must be controlled through appropriate treatment (Class I, Level C-LD). The use of protocols to control blood glucose levels may avoid both hypoglycemia and hyperglycemia as well as prevent large swings in blood glucose levels.…”
Section: Post-resuscitation Glucose Managementmentioning
confidence: 99%