Hypercholesterolemia Is Correlated With an Increased Risk of Idiopathic Sudden Sensorineural Hearing Loss

Abstract

A diagnosis of HCh may indicate an independent risk for ISSNHL. This finding suggests that an underlying vascular mechanism contributes to the development of ISSNHL. We suggest that physicians counsel patients with HCh to seek medical attention if they have hearing impairments, because they may also have an increased risk of developing ISSNHL.

Effect of comorbid diabetes and hypercholesterolemia on the prognosis of idiopathic sudden sensorineural hearing loss

“…Other studies have suggested an association between the risk of ISSNHL and the personal cardiovascular risk factors of HTN and Hch; however, these findings are controversial . Some researchers have reported a negative effect of comorbid HTN, but others have reported no effect .…”

The correlation between lipoprotein ratios and hearing outcome in idiopathic sudden sensorineural hearing loss patients

“…Several prognostic factors are reported to predict the outcome of hearing recovery for ISSNHL patients, including age, the presence or absence of vertigo, the type and severity of hearing loss, hypertension, the shape of the audiogram and the timeliness of initial treatment . Recently, some biochemical parameters have been indicated as prognostic factors, including hyperglycaemia, platelet wide length, neutrophil counts and hypercholesterolaemia …”

“…Some reports have proposed that hyperlipidaemia is correlated with an increased risk of ISSNHL . Although several articles have suggested that hypercholesterolaemia is a prognostic factor for ISSNHL, these assertions remain controversial .…”

Increased Risk of Sudden Sensorineural Hearing Loss in Patients With Osteoporosis: A Population-based, Propensity Score-matched, Longitudinal Follow-Up Study

“…Patients who had at least three ambulatory medical care visits and a principle diagnosis of SSNHL provided by an otolaryngologist in the referral teaching hospitals and tertiary referral medical centers to validate the diagnosis, which might be expected to provide adequate diagnostic accuracy. This method of identifying these diseases has been used extensively in various studies of Taiwan National Health Insurance Research Database, and many articles have been published (32)(33)(34). Another limitation is the difficulty in documenting the finer clinical details, such as cigarette smoking, alcohol consumption, family history, noise exposure, and changes in BMD in the analysis.…”