Hypercapnia during latrogenically Induced Metabolic Alkalosis

Perez-Guerra, Francisco

doi:10.1378/chest.65.1.108

Chest

1974

DOI: 10.1378/chest.65.1.108

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Hypercapnia during latrogenically Induced Metabolic Alkalosis

Francisco Perez-Guerra

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1977

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“…administration of sodium bicarbonate. However, hypoventilation in patients with metabolic alkalosis has been reported recently (Tuller and Mehdi, 1971;Steer et al, 1972;Perez-Guerra, 1974). In order to study adequately the effects of drugs on respiration, the respiratory response to carbon dioxide (CO 2 ) should be assessed.…”

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confidence: 99%

Effect of the Acute Administration of Sodium Bicarbonate on Respiration in the Presence of Hyperoxia

Nishino

Hata

Sakakibara

et al. 1977

British Journal of Anaesthesia

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The effects, on respiration, of the acute administration of sodium bicarbonate were studied in 10 normal subjects. Carbon dioxide responses curves and tidal volume v. PCO2 relationships were obtained under hyperoxic conditions using a closed-circuit breathing system. During alkalosis, a decrease in the slope, and a displacement of the response curves to the right, were observed. These findings indicate that metabolic alkalosis, induced acutely by the administration of sodium bicarbonate, alters the respiratory response to carbon dioxide and that sodium bicarbonate may have a depressant effect on respiration.

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mentioning

confidence: 99%

Effect of the Acute Administration of Sodium Bicarbonate on Respiration in the Presence of Hyperoxia

Nishino

Hata

Sakakibara

et al. 1977

British Journal of Anaesthesia

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Respiratory Failure

Martin

1977

Medical Clinics of North America

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Hypercapnia during latrogenically Induced Metabolic Alkalosis

Cited by 2 publications

References 3 publications

Effect of the Acute Administration of Sodium Bicarbonate on Respiration in the Presence of Hyperoxia

Effect of the Acute Administration of Sodium Bicarbonate on Respiration in the Presence of Hyperoxia

Respiratory Failure

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