Hydroxyapatite Surface Coatings for Biomaterials: A Report of a Multi-Centre Investigation–Brite-Euram Project BREU/0172C

Hastings, G.W.; Morrey, S.; Davies, Martin; Monteiro, F.J.; Barbosa, Mário A.; Sousa, Susana R.; Ribeiro, Cláudia; Reis, Rui L.; Leali, P. Tranquilli; Merolli, Antonio; Muster, D.; Demri, B.; Sousa, Mário de; Coita, A.J.; Santos, Mónica S.F.; Arosa, F.; Faleiro, C.; Anderson, D.; Evans, Peter; Harrison, P. L.

doi:10.1016/b978-0-08-042144-5.50036-4

Cited by 2 publications

(2 citation statements)

References 3 publications

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“…An in vivo study showed that plasma sprayed crystalline HA coatings could give rise to fragmented bulky particles. 36 Since PLD HA coatings are much thinner than plasma-sprayed HA coatings that are normally 50 m thick, a partial failure of the coating will not be as catastrophic as that of plasmasprayed HA coatings. The smaller gap between the implant substrate and bone and the smaller and fewer coating fragments make it easier for the surrounding tissue to accommodate the implant.…”

Section: Discussionmentioning

confidence: 99%

“…35,36 Because the saline solution was controlled to have a pH of 7.4, it is reasonable to assume that the dissolution of the coating came largely from the non-HA crystalline phases and amorphous phase, which also led to the significant reprecipitation. The HA/Ti peak ratio in XRD patterns decreased early in the immersion test, probably because the dissolution was dominant in the dissolution/reprecipitation process in the earlier period.…”

Section: Discussionmentioning

confidence: 99%

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The study of surface transformation of pulsed laser deposited hydroxyapatite coatings

Zeng

Lacefield

2000

J. Biomed. Mater. Res.

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Hydroxyapatite (HA) coatings generally exhibit very good biocompatibility owing to their compositional resemblance to the natural hard tissue and to bioactive properties that are directly related to surface transformations in physiological fluids. In this study, two types of porous HA coatings produced with pulsed laser deposition were tested with respect to their dissolution/reprecipitation in a semidynamic simulated physiological solution. Coatings with higher porosity produced with a 355-nm wavelength laser exhibited significant reprecipitation earlier than those produced with a 266-nm wavelength laser. The dissolution of the non-HA phases played a major role in the reprecipitation of HA-like material as indicated by X-ray diffraction (XRD). The coatings' Ca/P ratio became closer to the theoretical value of HA. The newly formed HA had imperfect crystal structure and/or small crystal size as suggested by XRD. The reprecipitation resulted in a very dense morphology as shown by scanning electron microscopy, suggesting a mechanically strong structure after reprecipitation. Despite undergoing dissolution and reprecipitation, the coatings showed sufficient stability in the solution, as XRD and energy-dispersive X-ray studies indicated no significant loss of the coatings. The stability of these HA coatings and their ability to cause reprecipitation of HA in the simulated physiological solution showed the potential of these coatings for clinical applications.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The study of surface transformation of pulsed laser deposited hydroxyapatite coatings

Zeng

Lacefield

2000

J. Biomed. Mater. Res.

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Image-Processing Techniques Applied to the Study of the Musculoskeletal System and Its Interactions with Biomaterials

Merolli¹,

Leali²

2000

MRS Bull.

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Over the past decade, orthopedic surgery and related research have made increasing use of the opportunities offered by computers. Many clinical and research procedures rely on medical images (e.g., x-ray films and histology) and their numerical evaluation (e.g., geometric analysis and surface metrology). This has led to the development of computer applications in orthopedics, with computer graphics playing a fundamental role. The image-processing field has also been studied in greater depth, with a view toward enhancing systems automation.Image processing relies on capturing measurable variations in some image parameters (e.g., light intensity, color, and signal-to-noise ratio). The extracted numerical values then can be used to modify the source image. From this definition, image processing can be considered a measurement technique, and in this light it has been introduced into histomorpho-metrical practice.Image processing speeds up routine analysis procedures by evaluating, in a less tedious and quicker way, a greater number of images, parameters, or both. Semiautomated computerized image-processing systems have been in use for a long time, based on computer-assisted analysis of objects whose contours were tracked manually by a digitizing cursor. Histological images were, generally, projected from the microscope over a digitizing tablet, with the operator visually recognizing the structure of interest and picking up its contours. The critical advance brought to histomorphometry by semiautomated techniques has been the practical measurement of surface-related parameters.

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Hydroxyapatite Surface Coatings for Biomaterials: A Report of a Multi-Centre Investigation–Brite-Euram Project BREU/0172C

Cited by 2 publications

References 3 publications

The study of surface transformation of pulsed laser deposited hydroxyapatite coatings

The study of surface transformation of pulsed laser deposited hydroxyapatite coatings

Image-Processing Techniques Applied to the Study of the Musculoskeletal System and Its Interactions with Biomaterials

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