Hydroquinone increases the frequency of micronuclei in a dose-dependent manner in mouse bone marrow

Electrochemical study for the simultaneous determination of phenolic compounds and emerging pollutant using an electroanalytical sensing system based on carbon nanotubes/surfactant and multivariate approach in the optimization

“…Hydroquinone is a phenolic compound naturally found in wood, tobacco smoke, coal tar, crude oil, and other materials. Due to its ability to inhibit the tyrosinase (melanin production participant) and facilitate degradation of melanosomes (intracellular corpuscles of melanin store), HQ is widely used as active principle in creams used for skin bleaching [8], but some studies have reported the cancerous alteration in mouse bone after administration of doses of hydroquinone [9]. As mentioned, these compounds have ambiguous behavior, and therefore, their (eco)toxicological effect on the environment and human health is still not clearly elucidated.…”

Simultaneous determination of hydroquinone and catechol using covalent layer-by-layer self-assembly of carboxylated-MWNTs

“…HQ may cause fatigue, headache, kidney damage, and CC may cause liver function decrease [2], [3]. The accurate determination of HQ and CC is needed urgently.…”

Selective Detoxification of Phenols by Pichia pastoris and Arabidopsis thaliana Heterologously Expressing the PtUGT72B1 from Populus trichocarpa

“…They can induce genotoxic [1], carcinogenic [2], and immunotoxic [3] effect. Phenol has been included in the lists of 11 priority pollutants by the US Environmental Protection Agency and the European Union.…”