Hydrophobic acrylic and plate-haptic silicone intraocular lens implantation in diabetic patients

Elgohary, Mostafa; Hollick, Emma J.; Bender, Lloyd; Heatley, Catherine J.; Wren, Siobhan; Boyce, J.F.; Missotten, Tom; Spalton, David J.; Dowler, Jonathan

doi:10.1016/j.jcrs.2006.01.106

Cited by 8 publications

(2 citation statements)

References 33 publications

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“…Hydrophobic lens material has lower PCO and ND: YAG laser treatment rate than the hydrophilic lens. [20212223] Hydrophilic lens used in this study had 360° square edge, which has been reported to prevent PCO. [13] The only remaining factor of this study is the incidence of multiple striae, leading to the PCO development.…”

Section: Discussionmentioning

confidence: 99%

Postoperative posterior capsular striae and the posterior capsular opacification in patients implanted with two types of intraocular lens material

Joshi

2017

Indian J Ophthalmol

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Aim:To evaluate the incidence of postoperative posterior capsular striae (PCS) and its influence on posterior capsular opacification (PCO) in patients implanted with two types of lens material.Setting:Tertiary eye care center in central rural India.Study Design:A prospective, observational, nonrandomized study.Materials and Methods:The study included 1247 patients having age-related cataract scheduled for removal by phacoemulsification technique and implantation of hydrophilic or hydrophobic intraocular lens (IOL). Demographic profile, nuclear grading, axial length, and IOL power were noted. Details of PCS were noted on the 1st postoperative day in patients with clear cornea. Postoperative follow-up was ensured to study the status of PCS and development of PCO.Results:The overall incidence of PCS was 19.8% (247 out of 1247 eyes). Out of 1247 patients, 641 patients (51.4%) had hydrophilic IOL implantation and 201 eyes had PCS (31.4%) and 606 patients (48.6%) had hydrophobic IOL implantation and 46 eyes had PCS (7.6%), P = 0.04. Three and more striae were seen in 119 eyes (119/641, 18.6%) in hydrophilic group and 4 eyes (4/606, 0.66%) in hydrophobic group. Sixty-two eyes (62/201, 30.9%) in hydrophilic group with multiple PCS were reported with persistent striae after 6 months of surgery. Two eyes in hydrophobic group had persistent striae even after 3 years of follow-up. Evaluation of PCO score of the hydrophilic group was 0.6 whereas of the hydrophobic group was 0.1 (P = 0.04). Ten patients of the hydrophilic group only required neodymium-doped yttrium aluminum garnet (ND: YAG) laser capsulotomy.Conclusion:The incidence of PCS was higher in hydrophilic than hydrophobic IOLs. Multiple PCS persisting in patients beyond 6 months after operation should be followed up for early development of PCO, particularly in patients implanted with hydrophilic IOL.

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Section: Discussionmentioning

confidence: 99%

Postoperative posterior capsular striae and the posterior capsular opacification in patients implanted with two types of intraocular lens material

Joshi

2017

Indian J Ophthalmol

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“…It has been observed to be the lowest with acrylic IOLs (10). The incidence of ACO and contraction is high in eyes with retinitis pigmentosa (11) and in diabetic patients (12). Werner et al have clinically graded ACO from 0 to IV (10).…”

Section: Anterior Capsule Opacification (Aco)mentioning

confidence: 99%

Post-operative Capsular Opacification: A review

Vasavada,

Raj,

Kaid

et al. 2007

Int. J Biomed Sci.

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Post-operative capsular opacification is a multifactorial physiological consequence of cataract surgery. Opacification involving the central posterior capsule has a significant impact on high and low contrast acuity and low contrast sensitivity. The assessment of Posterior Capsule Opacification (PCO) on cadaver eyes, experimental studies, culture models and in clinical studies has provided an understanding of its pathogenesis. The proliferation, migration and abnormal differentiation of residual lens epithelial cells and fibers in the capsular bag have been implicated in the pathogenesis of PCO. The incidence and severity of PCO correlates to the meticulous use of surgical techniques, IOL optic edge designs and IOL materials. This article summarizes the clinical studies with recommendations for retarding the development of central PCO. It discusses experiments with pharmacological agents broadly categorized as anti-inflammatory, immuno-modulating, antiproliferative, antiadhering, antitransdifferentiating agents for the prevention of PCO. These studies will remain critical for future endeavors undertaken for eradication of PCO.

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On the mechanisms of biocompatibility

2008

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Hydrophobic acrylic and plate-haptic silicone intraocular lens implantation in diabetic patients

Abstract: In diabetic patients, hydrophobic acrylic IOLs can lead to an increased flare in the early postoperative period but they seem to be more favorable than plate-haptic silicone IOLs because the latter lead to more PCO.

Cited by 8 publications

References 33 publications

Postoperative posterior capsular striae and the posterior capsular opacification in patients implanted with two types of intraocular lens material

Postoperative posterior capsular striae and the posterior capsular opacification in patients implanted with two types of intraocular lens material

Post-operative Capsular Opacification: A review

On the mechanisms of biocompatibility

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