Hydrolyzed Protein Diets for Dogs and Cats

Cave, Nick

doi:10.1016/j.cvsm.2006.08.008

Cited by 72 publications

(60 citation statements)

References 72 publications

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“…The optimal diets for food elimination were selected according to the results of the IgE and lymphocyte proliferation tests as well as individual diet history, palatability, and dog owner's preference. Conversely, when clinical signs were seasonal, CAD was suspected, but the food elimination was performed with a low-allergenic commercial diet of either Prescription Diet z/d ULTRA Allergen-free Canine [1,2] or Aminoprotect Care (Nosan Corporation, Tsukuba, Ibaraki, Japan) [22].…”

Section: Methodsmentioning

confidence: 99%

Flow Cytometric Analysis of Lymphocyte Proliferative Responses to Food Allergens in Dogs with Food Allergy

Fujimura

Masuda

Hayashiya

et al. 2011

The Journal of Veterinary Medical Science

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ABSTRACT. Two different allergy tests, antigen-specific immunoglobulin E quantification (IgE test) and flow cytometric analysis of antigen-specific proliferation of peripheral lymphocytes (lymphocyte proliferation test), were performed to examine differences in allergic reactions to food allergens in dogs with food allergy (FA). Thirteen dogs were diagnosed as FA based on clinical findings and elimination diet trials. Seven dogs clinically diagnosed with canine atopic dermatitis (CAD) were used as a disease control group, and 5 healthy dogs were used as a negative control group. In the FA group, 19 and 33 allergen reactions were identified using the serum IgE test and the lymphocyte proliferation test, respectively. Likewise, in the CAD group, 12 and 6 allergen reactions and in the healthy dogs 3 and 0 allergen reactions were identified by each test, respectively. A significant difference was found between FA and healthy dogs in terms of positive allergen detection by the lymphocyte proliferation test, suggesting that the test can be useful to differentiate FA from healthy dogs but not from CAD. Both tests were repeated in 6 of the dogs with FA after a 1.5-to 5-month elimination diet trial. The IgE concentrations in 9 of 11 of the positive reactions decreased by 20-80%, whereas all the positive reactions in the lymphocyte proliferation test decreased to nearly zero (P<0.05), suggesting that lymphocytes against food allergens may be involved in the pathogenesis of canine FA.

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Section: Methodsmentioning

confidence: 99%

Flow Cytometric Analysis of Lymphocyte Proliferative Responses to Food Allergens in Dogs with Food Allergy

Fujimura

Masuda

Hayashiya

et al. 2011

The Journal of Veterinary Medical Science

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“…Food allergens with a molecular mass of more than 10 kDa can bind to IgE antibodies on the surfaces of mast cells, resulting in the cross-linking of IgE and Fcε receptors, as well as subsequent degranulation and activation of mast cells [3,30,35]. The cross-linking of Fcε receptors with food allergens does not occur when the molecular weight of the food allergens is less than 10 kDa.…”

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confidence: 99%

“…, Jun ISHIHARA 2) , Kenichi MASUDA 3) , Nobutaka YASUDA 3) , Keitaro OHMORI 4) , Masahiro SAKAGUCHI 1) , Yasuhiro ASAMI 2) and Hajime TSUJIMOTO 2) Adverse food reaction (AFR) in dogs is associated with intake of various food ingredients or food additives [20,30,35]. Elicitation of type I hypersensitivity responses to food allergens has been implicated at least in part in the pathogenesis of AFR [11][12][13].…”

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confidence: 99%

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Clinical Efficacy of a Novel Elimination Diet Composed of a Mixture of Amino Acids and Potatoes in Dogs with Non-Seasonal Pruritic Dermatitis

Kawarai

Ishihara²,

Masuda

et al. 2010

The Journal of Veterinary Medical Science

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ABSTRACT. There has been a need for improvement of the elimination diet used for diagnosis of adverse food reaction (AFR) in dogs. Recently, a novel elimination diet composed of a mixture of amino acids and potatoes was developed. We evaluated the efficacy of the elimination diet for diagnosis of AFR in dogs. Twenty dogs that were suspected to have allergic dermatitis were enrolled in a 2-month food elimination trial using the diet. Before and after the trial, the clinical symptoms were evaluated based on the change in canine atopic dermatitis extent and severity index (CADESI), pruritus score and medication score. Of the 20 dogs, 15 completed the food elimination trial. The remaining 5 dogs were removed from the trial because of diet unpalatability, skin disease progression or diarrhea. On the basis of evaluation of the clinical scores, we observed that the clinical symptoms improved in 11 of the 15 dogs that completed the food elimination trial. Provocative challenge was performed in 10 of the 11 dogs that showed improvement in their clinical symptoms. Of the 10 dogs, 7 were diagnosed as having AFR against food ingredients such as pork, beef, chicken and wheat because their skin symptoms reappeared after intake of these ingredients. The results of the food elimination trial and the provocative challenge indicated the usefulness of the novel elimination diet for diagnosis of AFR.KEY WORDS: adverse food reaction, canine, elimination diet.

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“…Las proteínas con capacidad antigénica tienen una masa molecular entre 10 y 70 kDa y dietas con proteínas hidrolizadas por debajo de 10 kDa son efectivas para la reducción de la sintomatología de las alergias alimentarias en animales de compañía (Cave, 2006). Las proteínas de la soja con capacidad antigénica se encuentran entre 20 y 68 kDa .…”

Section: Los Antígenos Dietarios En El Desteteunclassified

Antigenicidad de piensos y materias primas proteicas en conejos

Cano¹,

Luís²

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Hydrolyzed Protein Diets for Dogs and Cats

Cited by 72 publications

References 72 publications

Flow Cytometric Analysis of Lymphocyte Proliferative Responses to Food Allergens in Dogs with Food Allergy

Flow Cytometric Analysis of Lymphocyte Proliferative Responses to Food Allergens in Dogs with Food Allergy

Clinical Efficacy of a Novel Elimination Diet Composed of a Mixture of Amino Acids and Potatoes in Dogs with Non-Seasonal Pruritic Dermatitis

Antigenicidad de piensos y materias primas proteicas en conejos

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