Hydrocortisone induce bradyarrhythmias: a case report

Abstract

<p class="abstract">Steroids are common drugs used in various disorders and are also known to have adverse effects on all systems. In cardiovascular system, it can cause various conduction abnormalities in the heart. In this report we describe recurrence of bradycardia in a patient of urosepsis after using hydrocortisone<span lang="EN-IN">. </span></p>

An uncommon side effect of a very commonly used medication: A case report on hydrocortisone‐induced bradycardia

“… 1 Another postulated mechanism is that high‐dose corticosteroid altered the sensitivity of SA node to catecholamine. 2 According to a study by Vasheghani‐Farahani et al, (2001) which involved 52 hospitalized patients with acute flare of multiple sclerosis and was treated with high‐dose corticosteroids therapy, sinus bradycardia was observed in 41.9% of the patients. 3 There are several predisposing factors to developing corticosteroid‐induced bradycardia, including a rapid rate of intravenous infusion and the presence of underlying cardiac or renal diseases, and electrolyte imbalances will increase the risk of developing this adverse effect.…”

“…This, in turn, activates the low‐pressure baroreceptors and resulted in bradycardia 1 . Another postulated mechanism is that high‐dose corticosteroid altered the sensitivity of SA node to catecholamine 2 . According to a study by Vasheghani‐Farahani et al, (2001) which involved 52 hospitalized patients with acute flare of multiple sclerosis and was treated with high‐dose corticosteroids therapy, sinus bradycardia was observed in 41.9% of the patients 3 …”