Hydrazine exposure: A near-infrared ICT-based fluorescent probe and its application in bioimaging and sewage analysis

A lysosome-targetable fluorescent probe for the ratiometric detection of formaldehyde in living cells and in vivo

“…Neutral filter paper was immersed in SWJT-6 (1.0 mM) solution, and then formaldehyde was detected at different concentrations. 17 As shown in Fig. 4, the test strip of SWJT-6 was brownish red under visible light.…”

A resorufin-based fluorescent probe for hydrazine detection and its application in environmental analysis and bioimaging

“…Hydrazine (N 2 H 4 ) is a colorless, oily, alkaline, and reducible liquid that is widely used in many elds as a foaming agent, polymerization inhibitor, agrochemical, rocket propellant as well as antiseptic agent in water treatment. [1][2][3] However, because it is mutagenic, teratogenic, carcinogenic, and highly toxic, the widespread use of hydrazine will inevitably lead to serious pollution problems of air, water, soil and other aspects. [4][5][6] Although endogenous hydrazine is not synthesized in organisms, some dietary supplements and certain drugs, such as the anti-tuberculosis drug isoniazid (INH), can be enzymatically digested in the liver to synthesize hydrazine.…”

Near-Infrared Fluorescent Probe with a Large Stokes Shift for Detection of Hydrogen Sulfide in Food Spoilage, Living Cells, and Zebrafish

“…Among the reported methods for detecting H 2 S, the fluorescence-based assay has attracted public attention because of its real-time detection, simplicity of implementation, and nondestructive analysis, − and the fluorescent method has been applied in various areas such as food examination, biological imaging, and environmental monitoring. − For instance, Yan’s group reported a turn-on fluorescent probe which could target mitochondria, image H 2 S in living cells, and judge the H 2 S level in real water samples and beer; Xiao et al developed a color and fluorescence turn-on probe for monitoring the spoilage of eggs and fish; and Wang et al constructed a ratiometric and mitochondria-targeted probe, which not only could image endogenous and exogenous H 2 S in HeLa cells but also could measure the freshness of raw meat on-site . Although several fluorescent probes have been reported for detecting H 2 S, however, the majority of them is unable to visualize H 2 S in vivo primarily on account of their short emission wavelength (<650 nm), and only a few of the reported probes could detect H 2 S gas.…”