2015
DOI: 10.1111/itor.12167
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Hybridizations of GRASP with path relinking for the far from most string problem

Abstract: Among the sequence selection and comparison problems, the far from most string problem (FFMSP) is one of the computationally hardest with applications in several fields, including molecular biology where one is interested in creating diagnostic probes for bacterial infections or in discovering potential drug targets. In this paper, we describe several heuristics that hybridize GRASP with different path‐relinking strategies, such as forward, backward, mixed, greedy randomized adaptive forward, and evolutionary … Show more

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Cited by 15 publications
(6 citation statements)
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References 35 publications
(60 reference statements)
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“…Annotated bibliographies of GRASP appeared in Resende (2009a, 2009b). A recent application of GRASP appeared in Ferone et al (2016).…”
Section: Grasp With Path-relinking Heuristicmentioning
confidence: 99%
“…Annotated bibliographies of GRASP appeared in Resende (2009a, 2009b). A recent application of GRASP appeared in Ferone et al (2016).…”
Section: Grasp With Path-relinking Heuristicmentioning
confidence: 99%
“…Furthermore, they declared that the combination of PR with SS gave the best results. Recently, in [26,27], path relinking is also hybridized with other heuristics showing good results. Based on these results, we were motivated for hybridizing this procedure within the evolutionary framework.…”
Section: A Hybrid Evolutionary Algorithm With Path Relinkingmentioning
confidence: 99%
“…The recent application in a hard combinatorial problem coming from biological systems, which can be found in Ferone et al. (). Here, we will develop a GRASP heuristic enriched with VND and a Shaking operation in order to prevent being trapped in local optima.…”
Section: Graspmentioning
confidence: 99%
“…GRASP has been successfully applied to several problems arising in telecommunications, such as optical systems (Duarte et al, 2014), WDM systems (Wu et al, 2015), and WAN design (Robledo Amoza, 2005), and many other fields of knowledge. The recent application in a hard combinatorial problem coming from biological systems, which can be found in Ferone et al (2016). Here, we will develop a GRASP heuristic enriched with VND and a Shaking operation in order to prevent being trapped in local optima.…”
Section: Graspmentioning
confidence: 99%