Hybrid gold atomic cluster–cobalt oxide scaffolds for dual tandem electrocatalytic sensing of cysteine

Nambiar, Sindhu R.; Prathish, K.P.; Karthik, G.M.; Rao, T. Prasada

doi:10.1016/j.bios.2011.03.011

Cited by 22 publications

(16 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To increase the sensitivity for Cys determination, a scaffold combining AuNCs and CoO was synthesized by Nambiar et al. [ 32 ]. These scaffold naonoclusters showed a large number of available binding sites and could be used in electrocatalysis studies.…”

Section: Amino Acids and Enzymes Biosensingmentioning

confidence: 99%

“…Moreover, there is also an obvious increasing trend in the use of scaffold-based materials in biosensing. Scaffolds or nano-scaffold-based materials have mostly been employed for the detection and quantification of analytes, such as cancer biomarkers [ 3 , 20 ], glucose [ [21] , [22] , [23] ], pharmaceutical compounds [ [24] , [25] , [26] ], hydrogen peroxide [ 27 ], neurotransmitters [ [28] , [29] , [30] ], amino acids [ 31 , 32 ], or inorganic ions [ 33 ].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Applications of scaffold-based advanced materials in biomedical sensing

Sarkhosh-Inanlou

Shafiei‐Irannejad

Azizi

et al. 2021

TrAC Trends in Analytical Chemistry

View full text Add to dashboard Cite

There have been many efforts to synthesize advanced materials that are capable of real-time specific recognition of a molecular target, and allow the quantification of a variety of biomolecules. Scaffold materials have a porous structure, with a high surface area and their intrinsic nanocavities can accommodate cells and macromolecules. The three-dimensional structure (3D) of scaffolds serves not only as a fibrous structure for cell adhesion and growth in tissue engineering, but can also provide the controlled release of drugs and other molecules for biomedical applications. There has been a limited number of reports on the use of scaffold materials in biomedical sensing applications. This review highlights the potential of scaffold materials in the improvement of sensing platforms and summarizes the progress in the application of novel scaffold-based materials as sensor, and discusses their advantages and limitations. Furthermore, the influence of the scaffold materials on the monitoring of infectious diseases such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and bacterial infections, was reviewed.

show abstract

Section: Amino Acids and Enzymes Biosensingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Applications of scaffold-based advanced materials in biomedical sensing

Sarkhosh-Inanlou

Shafiei‐Irannejad

Azizi

et al. 2021

TrAC Trends in Analytical Chemistry

View full text Add to dashboard Cite

show abstract

“…Currently, cobalt oxide (Co 3 O 4 ) nanostructures have been studied widely and received more attention from the scientific community, thus effective efforts have been made for the synthesis of various morphologies . The cobalt oxide has been used in different applications such as battery materials , catalysis , magnetic storage materials , sensors and biosensors .…”

Section: Introductionmentioning

confidence: 99%

“…They interact with nanomaterials by covalent coupling, electrostatic attraction, and physical adsorption. Considerable efforts have been put forward in the recent years to prepare metal oxide nanostructures in the presence of amino acids such as ZnO , TiO 2 , ZrO 2 , CuO , SnO 2 . To the best of our knowledge, there is no investigation carried out in detail using substances with bifunctional activity such as amino acids, whose isoelectric pH remains well controlled, to obtain functional nanostructured cobalt oxide.…”

Section: Introductionmentioning

confidence: 99%

The Synthesis of Functional Cobalt Oxide Nanostructures, and their Sensitive Glucose Sensing Application

et al. 2016

View full text Add to dashboard Cite

In this study, a novel approach is adapted for the synthesis of new nanostructures of cobalt oxide (Co3O4) by low temperature aqueous chemical growth method in the presence of water soluble amino acids such as L‐arginine, L‐aspartic acid, L‐isoleucine, L‐leucine, L‐serine and L‐threonine. The synthesized nanostructures were characterized by X‐ray diffraction (XRD), scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM). The nanostructures exhibit well defined morphology and are of high purity. To explore the potential application of the prepared nanostructures of cobalt oxide, the non‐enzymatic glucose sensor is developed by modifying the glassy carbon electrode. Serine assisted cobalt oxide nanostructures showed excellent sensitivity of 4169.00 μA/mM cm2, wide linear range of 0.01 mM to 20 mM and detection limit was estimated as 0.001 mM (S/N=3). The analytical parameters for the serine assisted cobalt oxide nanostructures based glucose sensor were evaluated and it was found that the sensor is highly selective, reproducible, repeatable, reversible, and stable. Finally, the practical application of the serine assisted cobalt oxide nanostructures based glucose sensor was examined by measuring the glucose concentrations from real human blood samples.

show abstract

“…3 Gold nanoclusters (AuNCs) exhibit fascinating features, including ease of synthesis, good water solubility, low toxicity, surface functionalities, biocompatibility and excellent stability. 4 Gold nanoclusters formed in the presence of cobalt oxide have been successfully employed for electrochemical sensing of cysteine 5 and a catechol sensor was developed using poly (3,4-ethylenedioxythiophene) modified with gold clusters on a glassy carbon electrode. 6 Chitosan (b-1,4-linked poly D-glucosamine), derived from the deacetylation of chitin, is the second most abundant biopolymer in nature after cellulose and is inexpensive, displays excellent film forming ability, biocompatible, nontoxic, possesses high mechanical strength, and amenable to chemical modification.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical synthesis of a gold atomic cluster–chitosan nanocomposite film modified gold electrode for ultra-trace determination of mercury

Aneesh

Nambiar

Rao

et al. 2014

Phys. Chem. Chem. Phys.

Self Cite

View full text Add to dashboard Cite

Gold atomic cluster based nanocomposites are important in the field of energy and sensing applications due to their interesting optical, electronic, chemical and catalytic properties. In the present study a chitosan stabilized gold atomic cluster nanocomposite was synthesised by a simple electrochemical technique based on the anodic dissolution of a gold electrode in the presence of a cationic surfactant, cetyl trimethyl ammonium bromide (CTAB), and a biopolymer, chitosan, on a gold electrode. The gold clusters formed were characterized by DLS, TEM, MALDI-TOF-MS, XPS, fluorescence and cyclic voltammetry. The developed gold atomic cluster-chitosan (AuAC-Chit) nanocomposite modified gold electrode was highly sensitive and selective for the electrochemical detection of Hg(ii) ions. It offers a wider calibration range of 10(-14)-10(-7) M with a limit of detection (LOD) of 0.8 × 10(-14) M and a limit of quantification (LOQ) of 6.6 × 10(-14) M, much below the guideline value of 1 × 10(-8) M stipulated by United States Environmental Protection Agency (USEPA), accompanied by a good precision of 1.06% for 10(-13) M of Hg(ii). The designed sensor is selective to Hg(ii) ions in the presence of other coexisting species.

show abstract

Hybrid gold atomic cluster–cobalt oxide scaffolds for dual tandem electrocatalytic sensing of cysteine

Cited by 22 publications

References 34 publications

Applications of scaffold-based advanced materials in biomedical sensing

Applications of scaffold-based advanced materials in biomedical sensing

The Synthesis of Functional Cobalt Oxide Nanostructures, and their Sensitive Glucose Sensing Application

Electrochemical synthesis of a gold atomic cluster–chitosan nanocomposite film modified gold electrode for ultra-trace determination of mercury

Contact Info

Product

Resources

About