Hybrid Gelatin Hydrogels in Nanomedicine Applications

Salahuddin, Bidita; Wang, Shuo; Sangian, Danial; Aziz, Shazed; Gu, Qi

doi:10.1021/acsabm.0c01630

Cited by 70 publications

(37 citation statements)

References 172 publications

(280 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Obtaining GEL from COL requires breaking the bonds that stabilize the structure from a pre-treatment by means of acids, bases or enzymes. In this sense, type A GEL (isoelectric point 8–9) is obtained after an acid treatment of COL, and type B GEL (isoelectric point 4–5) is obtained with an alkaline treatment [ 74 , 152 ]. The amines present in the lysine side chains help the GEL to adhere to the carboxyl groups of the tissue surface molecules [ 75 ].…”

Section: Methodsmentioning

confidence: 99%

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

et al. 2022

View full text Add to dashboard Cite

Nowadays, there are still numerous challenges for well-known biomedical applications, such as tissue engineering (TE), wound healing and controlled drug delivery, which must be faced and solved. Hydrogels have been proposed as excellent candidates for these applications, as they have promising properties for the mentioned applications, including biocompatibility, biodegradability, great absorption capacity and tunable mechanical properties. However, depending on the material or the manufacturing method, the resulting hydrogel may not be up to the specific task for which it is designed, thus there are different approaches proposed to enhance hydrogel performance for the requirements of the application in question. The main purpose of this review article was to summarize the most recent trends of hydrogel technology, going through the most used polymeric materials and the most popular hydrogel synthesis methods in recent years, including different strategies of enhancing hydrogels’ properties, such as cross-linking and the manufacture of composite hydrogels. In addition, the secondary objective of this review was to briefly discuss other novel applications of hydrogels that have been proposed in the past few years which have drawn a lot of attention.

show abstract

Section: Methodsmentioning

confidence: 99%

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Salahuddin et al prepared a light-controlled hydrogel. When exposed to light, the mesh of the hydrogel changes, altering the diffusion rate of the molecules being convenient for the controlled release of the drug [134]. Yang et al prepared an antiopal microsphere and used its nanoporous structure to load drugs injected into the joint cavity.…”

Section: Drug Delivery and Tissue Engineeringmentioning

confidence: 99%

Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering

Liu

Chen

et al. 2022

Gels

View full text Add to dashboard Cite

Hydrogel materials have great application value in biomedical engineering. Among them, photocrosslinked hydrogels have attracted much attention due to their variety and simple convenient preparation methods. Here, we provide a systematic review of the biomedical-engineering applications of photocrosslinked hydrogels. First, we introduce the types of photocrosslinked hydrogel monomers, and the methods for preparation of photocrosslinked hydrogels with different morphologies are summarized. Subsequently, various biomedical applications of photocrosslinked hydrogels are reviewed. Finally, some shortcomings and development directions for photocrosslinked hydrogels are considered and proposed. This paper is designed to give researchers in related fields a systematic understanding of photocrosslinked hydrogels and provide inspiration to seek new development directions for studies of photocrosslinked hydrogels or related materials.

show abstract

“…The key to DNA biosensors is the fusion of materials with specific probe DNA or single-stranded DNA (ssDNA) [ 103 ]. Gelatin can be a promising material for DNA biosensors due to its good biocompatibility, biodegradability, biological activity, exceptional cell/tissue attraction, and extraordinary physiochemical characteristics [ 104 ]. It has been reported that GelMA and DNA can be used as a biosensor for DNA hybridization [ 105 ].…”

Section: Conclusion and Future Outlookmentioning

confidence: 99%

Applications of Gelatin in Biosensors: Recent Trends and Progress

Guan

Huang

2022

Biosensors

View full text Add to dashboard Cite

Gelatin is a natural protein from animal tissue with excellent biocompatibility, biodegradability, biosafety, low cost, and sol–gel property. By taking advantage of these properties, gelatin is considered to be an ideal component for the fabrication of biosensors. In recent years, biosensors with gelatin have been widely used for detecting various analytes, such as glucose, hydrogen peroxide, urea, amino acids, and pesticides, in the fields of medical diagnosis, food testing, and environmental monitoring. This perspective is an overview of the most recent trends and progress in the development of gelatin-based biosensors, which are classified by the function of gelatin as a matrix for immobilized biorecognition materials or as a biorecognition material for detecting target analytes.

show abstract

Hybrid Gelatin Hydrogels in Nanomedicine Applications

Cited by 70 publications

References 172 publications

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

Novel Trends in Hydrogel Development for Biomedical Applications: A Review

Current Understanding of the Applications of Photocrosslinked Hydrogels in Biomedical Engineering

Applications of Gelatin in Biosensors: Recent Trends and Progress

Contact Info

Product

Resources

About