“…Regression of the hyaloid vessels is controlled by retinal neurons, astrocytes, and macrophages via oxygensensing and Wnt pathways (Kurihara et al, 2010; Lobov et al, 2005; Rao et al, 2013). If hyaloid vessels do not entirely regress, the persistence of the hyaloid vasculature is associated with poor retinal development and poor vision in neonates (JONES, 1963; Liu and Nathans, 2008; Saint-Geniez and D’Amore, 2004). The regression of the hyaloid vessels normally occurs in humans around mid-gestation and mice after birth.…”