Humoral immunity in the ewe 2. The effect of pregnancy on the primary and secondary antibody response to protein antigen

Reynolds, Gary; Griffin, J.F.T.

doi:10.1016/0165-2427(90)90032-n

Cited by 10 publications

(5 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, it has been shown that asymptomatic adult cattle and sheep may act as healthy carriers (de Graaf and others 1999) and may be a source of infection for their calves and lambs, especially when there is a periparturient increase in the output of oocysts. This increase is probably related to a change in the immunoreactivity of domestic ruminants during late pregnancy and lactation (Reynolds and Griffin 1990) and has been demonstrated in sheep (Xiao andothers 1994, Ortega-Mora andothers 1999), cows (Ralston and others 2003) and red deer (Skerrett and Holland 2001). Similar observations have been made with Giardia species infections in sheep (Xiao and others 1994) and cows (Ralston and others 2003).…”

supporting

confidence: 69%

Giardia duodenalis and Cryptosporidium parvum infections in adult goats and their implications for neonatal kids

et al. 2005

View full text Add to dashboard Cite

During the kidding season between January and April 2003, 10 farms were selected and divided into two groups of five. The farms in group A had had serious diarrhoeal illness and losses in neonatal kids the previous year, and there were Cryptosporidium parvum infections in kids associated with diarrhoea during the survey. On the farms in group B, there was no history of diarrhoeal disease the previous year and neither C parvum oocysts nor diarrhoea were detected in neonatal kids during the survey. Faecal samples were collected once from 10 adult goats aged between one and seven years on each farm. To assess more accurately the pattern of output of oocysts of C parvum and cysts of Giardia duodenalis by periparturient adult goats, one farm was selected from each group, faecal samples were collected weekly before and after kidding from 12 goats on the farm in group A and from 10 goats on the farm in group B. There was no significant difference in the prevalence of G duodenalis cysts between the group A farms (14 per cent) and the group B farms (12 per cent), and the numbers of cysts excreted ranged from 143 to 400 cysts per gram of faeces (cpg) on the group A farms and 72 to 334 cpg on the group B farms. There was a significant difference (P=0.03) in the prevalence of C parvum oocysts at the group level between the group A farms (20 per cent) and the group B farms (6 per cent). All the adult goats excreted cysts and oocysts at some date around the kidding period; the number of animals excreting cysts of G duodenalis or oocysts of C parvum increased when they gave birth, and seven to 10 times more cysts and oocysts were shed in the three weeks around kidding than in the period more than three weeks from kidding (P<0.001).

show abstract

supporting

confidence: 69%

Giardia duodenalis and Cryptosporidium parvum infections in adult goats and their implications for neonatal kids

et al. 2005

View full text Add to dashboard Cite

show abstract

“…This is in contrast to published findings where strong antibody responses to BSA, diphtheria toxin and tetanus toxin have been observed in mice following TCI. 1,2 It is noteworthy that, in contrast to published findings, 14 in the present experiments BSA proved to be a weak immunogen and did not induce systemic antibody responses when administered subcutaneously. It is likely that modifications to formulations or to the method of application of immunising mixtures to skin will be necessary before vaccines delivered by this route can induce protective immunity.…”

Section: Eu (Mean ± Sem)contrasting

confidence: 76%

Effect on systemic antibody concentrations of topical application of choleratoxin to skin of sheep

Cope

Colditz

2000

Aust Veterinary J

View full text Add to dashboard Cite

show abstract

“…Many researchers observed the relationship between immunization, pregnancy and lactation. In this respet, Reynolds and Griffin (1990) showed that the levels of immunoglobulin M (IgM) increased and continued in response to bovine serum albumin during pregnancy. Also, the observed increase in IgM concentration after 7 days of kidding was proved in ewes by Basim and Abed (2015), who reported a significant increase in IgM concentration in pregnant and lactating ewes in comparison with nonpregnant and non-lactating groups.…”

Section: Immunoglobulin M (Igm) Concentration Of Baladi and Shami Doesmentioning

confidence: 91%

“…Many workers noted a relationship between the immunization, pregnancy and lactation. Reynolds and Griffin (1990) showed that the immunoglobulin M levels (IgM) increased in reaction to bovine serum albumin during gestation. Secondary immunoglobulin G1 titers were significantly decreased in late gestation and during lactation whereas the lower immunoglobulin levels G2 were unchanged by gestation.…”

Section: Introductionmentioning

confidence: 99%

Effect of Immunological Responses of Baladi and Shami Does on Mortality Rate of their Offsprings during Post-Partum Period

Farid

Ibrahim

EL–Tonsy

et al. 2018

Journal of Animal and Poultry Production

View full text Add to dashboard Cite

The main goal of the present experiment is to scrutinize the effect of the maternal immunity on their kids and it's relation to neonatal mortality in Baladi and Shami goat's kids during post-partum period (1st month post-partum). This study was conducted at the Ras Sudr Research Station of the Desert Research center, South Sinai Governorate, Egypt. Fifty clinically healthy adult, 18 months old, estrus synchronized does of two breeds of goats were grouped in two groups according to their breed. The first group contained 25 Baladi does (21.27 kg average body weight) and the second group contained 25 Shami does (35.35 kg average body weight). All dams of both groups were naturally mated. All kids were left with their mothers during the study period (one month) and fed only with colostrum and maternal milk. White blood cells (WBCs) and its differential count, serum immunoglobulin M (IgM) and interleukin 6 (IL-6) concentrations were determined in both dams groups at pre-partum and post-partum and in their kids at the first month postpartum. Dead kids were dissected and spleens were prepared for histopathological studies. Results demonstrated that, Baladi dams showed insignificant increase in WBCs as compared to Shami does. It was obvious that, Baladi does showed insignificant increase in neutrophils and monocytes and insignificant decrease in lymphocytes in comparison with Shami does. Concerning physiological status, significant changes were observed among WBCs and its differential count of Baladi and Shami does during experimental period. Kid's WBCs and lymphocytes were insignificantly higher in Shami kids than in Baladi kids, while neutrophils and monocytes were insignificantly lower in Shami kids. Concerning post-partum days, there was a significant increase in the values of WBC, monocytes and neutrophils throughout the 30-days post-partum in both kids groups .The present study revealed that serum IgM was significantly higher in Baladi does (0.91 mg/ml) than in Shami does (0.40 mg/ml) by a percentage of 127.5%. IgM level was significantly increased during pregnancy status and the high level was recorded in late gestation (0.75 mg/ml). Maternal breed indicated a significant effect on kid's serum IgM concentration. IgM was significantly higher in Baladi kids (0.27 mg/ml) than in Shami kids (0.11 mg/ml) by a percentage of 145.45%. Serum IgM concentrations significantly increased during neonatal period. The overall mean for IL -6 was significantly higher in Shami does than in Baladi does by a percentage of 65.63%. Concerning the influence of physiological status, IL -6 level increased significantly at post-partum in Shami does while pregnancy period had no significant effect on IL -6 concentration in both breeds . The overall mean for IL-6 was significantly higher in Shami kids (27.22 pg/ml) than in Baladi kids (9.58 pg/ml) by a percentage of 184.13%. Serum IL-6 showed a significant reduction during neonatal period in kids on 0, 7, 14, 21 and 28 days, respectively. Histological alterations of kid's spleen revealed depl...

show abstract

Humoral immunity in the ewe 2. The effect of pregnancy on the primary and secondary antibody response to protein antigen

Cited by 10 publications

References 15 publications

Giardia duodenalis and Cryptosporidium parvum infections in adult goats and their implications for neonatal kids

Giardia duodenalis and Cryptosporidium parvum infections in adult goats and their implications for neonatal kids

Effect on systemic antibody concentrations of topical application of choleratoxin to skin of sheep

Effect of Immunological Responses of Baladi and Shami Does on Mortality Rate of their Offsprings during Post-Partum Period

Contact Info

Product

Resources

About