Humic acids as both matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and adsorbent for magnetic solid phase extraction

Zhao, Qingguo; Xu, Juntian; Yin, Jia; Feng, Yu‐Qi

doi:10.1016/j.aca.2015.07.040

Cited by 7 publications

(3 citation statements)

References 48 publications

(39 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sensitivity of the detection of oligosaccharides was significantly improved by using hydrazinonicotinic acid (HYNIC) as a MALDI matrix in an investigation by Jiao and co-workers . Zhao et al discovered that humic acids make effective matrixes by ionizing rhodamine B successfully with almost no interfering low mass ions . Work by Chen and colleagues demonstrated that a binary MALDI matrix made from carbon dots with 9-aminoacridine (9AA) ionized a wide variety of small molecules with excellent sensitivity and reproducibility.…”

Section: Traditional Ionization Methods For Msmentioning

confidence: 99%

“…164 Zhao et al discovered that humic acids make effective matrixes by ionizing rhodamine B successfully with almost no interfering low mass ions. 165 Work by Chen and colleagues demonstrated that a binary MALDI matrix made from carbon dots with 9-aminoacridine (9AA) ionized a wide variety of small molecules with excellent sensitivity and reproducibility. The binary matrix showed a marked improvement in ionization efficiency compared to 9AA alone.…”

Section: ■ Traditional Ionization Methods For Msmentioning

confidence: 99%

See 1 more Smart Citation

Advances in Ionization for Mass Spectrometry

Peacock¹,

Zhang

Trimpin

2016

Anal. Chem.

View full text Add to dashboard Cite

Section: Traditional Ionization Methods For Msmentioning

confidence: 99%

Section: ■ Traditional Ionization Methods For Msmentioning

confidence: 99%

Advances in Ionization for Mass Spectrometry

Peacock¹,

Zhang

Trimpin

2016

Anal. Chem.

View full text Add to dashboard Cite

“…Magnetic humic acid (MHA) was a novel nanomaterial, which could be applied as both an adsorbent and a matrix in MALDI-MS analysis. 117 HA, a kind of natural macromolecule compound, has a laser energy absorbing-transferring aromatic structure. 118,119 In addition, the unique adsorption abilities make HA a good candidate as an adsorbent, including chelation, charge transfer interaction, hydrogen bonding, hydrophobic and π-π interactions for enrichment of pesticides, polycyclic aromatic hydrocarbons (PAHs), heavy metal ions and chlorophenols.…”

Section: Inorganic Materials As Adsorbents For Enrichment Of Target M...mentioning

confidence: 99%

Recent advances in inorganic materials for LDI-MS analysis of small molecules

Shi

Deng

2016

Analyst

View full text Add to dashboard Cite

In this review, various inorganic materials were summarized for the analysis of small molecules by laser desorption/ionization mass spectrometry (LDI-MS). Due to its tremendous advantages, such as simplicity, high speed, high throughput, small analyte volumes and tolerance towards salts, LDI-MS has been widely used in various analytes. During the ionization process, a suitable agent is required to assist the ionization, such as an appropriate matrix for matrix assisted laser desorption/ionization mass spectrometry (MALDI-MS). However, it is normally difficult to analyze small molecules with the MALDI technique because conventional organic matrices may produce matrix-related peaks in the low molecular-weight region, which limits the detection of small molecules (m/z < 700 Da). Therefore, more and more inorganic materials, including carbon-based materials, silicon-based materials and metal-based materials, have been developed to assist the ionization of small molecules. These inorganic materials can transfer energy and improve the ionization efficiency of analytes. In addition, functionalized inorganic materials can act as both an adsorbent and an agent in the enrichment and ionization of small molecules. In this review, we mainly focus on present advances in inorganic materials for the LDI-MS analysis of small molecules in the last five years, which contains the synthetic protocols of novel inorganic materials and the detailed results achieved by inorganic materials. On the other hand, this review also summarizes the application of inorganic materials as adsorbents in the selective enrichment of small molecules, which provides a new field for the application of inorganic materials.

show abstract

Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

Abdelhamid

2019

Microchim Acta

View full text Add to dashboard Cite

Humic acids as both matrix for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and adsorbent for magnetic solid phase extraction

Cited by 7 publications

References 48 publications

Advances in Ionization for Mass Spectrometry

Advances in Ionization for Mass Spectrometry

Recent advances in inorganic materials for LDI-MS analysis of small molecules

Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

Contact Info

Product

Resources

About