Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

Abdelhamid, Hani Nasser

doi:10.1007/s00604-019-3770-5

Cited by 82 publications

(60 citation statements)

References 448 publications

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“…Zeolitic imidazolate frameworks (ZIFs), [ 1–11 ] a class of metal organic frameworks, [ 12,13 ] have been applied for several applications such as catalysis, biomedical, [ 14 ] and environmental‐related fields. ZIFs materials offer several advantages including large surface area, tunable pore size, active metal sites, and good thermal and chemical stability due to the strong coordination bonds between the metal centers and linker donating atoms such as ‐N‐.…”

Section: Introductionmentioning

confidence: 99%

“…Thus, several approaches were reported to reduce anthropogenic CO 2 concentration in the atmosphere. Applications of metal‐organic frameworks (MOFs), [ 4,3,13,28–34 ] including ZIFs for CO 2 adsorption are promising [ 22,35 ] for lowering the concentration of greenhouse gases in the atmosphere. [ 36–39 ] MOFs [ 40 ] have been applied as catalysts for the chemical fixation and photochemical reduction of CO 2 , [ 41 ] and as adsorbents.…”

Section: Introductionmentioning

confidence: 99%

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Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis

Abdelhamid

2020

Macro Chemistry & Physics

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Despite the great potential of two different pore regimes (hierarchical porous (HP) structure), HP‐zeolitic imidazolate frameworks‐8 (HPZIF‐8) can be efficient catalysts for hydrogen generation via hydride hydrolysis, and as adsorbents for CO2 gas adsorption. Herein, HPZIF‐8, and leaf‐like ZIF (ZIF‐L) are synthesized via a simple and environmentally friendly procedure using layered hydroxide nitrate of zinc (Z5HN) as a metal source and simple inorganic salt as a modulator. Z5HN nanosheets undergo topotactic transformation to simonkolleite (Zn5(OH)8Cl2·H2O) that can be converted to the pure phase of HPZIF‐8. The concentration of the salts tunes the textural properties of the final product. Applications of HPZIF‐8 and ZIF‐L for CO2 sorption exhibit excellent adsorption properties with increases of 25% due to the presence of cations in the frameworks. ZIF‐8 shows exceptional high catalytic activity for hydrogen generation via the hydrolysis of sodium borohydride. The simple synthesis of ZIF‐8 as well as their good performance as adsorbent and catalyst ensure the potential for industrial and commercial uses.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis

Abdelhamid

2020

Macro Chemistry & Physics

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“…Future studies will also address the benefits of other MS instrumentations and IMS analysis techniques such as e.g. nanoparticle-based surface assisted laser desorption ionization (LDI)-MS 49 , for the analysis of optically cleared tissue samples.…”

Section: Discussionmentioning

confidence: 99%

Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples

Blutke

Sun

et al. 2020

Sci Rep

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Light sheet fluorescence microscopy (LSFM) of optically cleared biological samples represents a powerful tool to analyze the 3-dimensional morphology of tissues and organs. Multimodal combinations of LSFM with additional analyses of the identical sample help to limit the consumption of restricted specimen and reduce inter-sample variation. Here, we demonstrate the proof-of-concept that LSFM of cleared brain tissue samples can be combined with Matrix Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging (MALDI-MSI) for detection and quantification of proteins. Samples of freshly dissected murine brain and of archived formalin-fixed paraffin-embedded (FFPE) human brain tissue were cleared (3DISCO). Tissue regions of interest were defined by LSFM and excised, (re)-embedded in paraffin, and sectioned. Mouse sections were coated with sinapinic acid matrix. Human brain sections were pre-digested with trypsin and coated with α-cyano-4-hydroxycinnamic acid matrix. Subsequently, sections were subjected to MALDI-time-of-flight (TOF)-MSI in mass ranges between 0.8 to 4 kDa (human tissue sections), or 2.5–25 kDa (mouse tissue sections) with a lateral resolution of 50 µm. Protein- and peptide-identities corresponding to acquired MALDI-MSI spectra were confirmed by parallel liquid chromatography tandem mass spectrometry (LC–MS/MS) analysis. The spatial abundance- and intensity-patterns of established marker proteins detected by MALDI-MSI were also confirmed by immunohistochemistry.

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“…MS depends on the ionization of the viral contents, e.g., protein or RNA. Soft ionization techniques such as matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) are promising for direct detection of the intact virus [25,41,76,[249][250][251][252][253][254][255][256]. Nanoparticles are essential as the surface for MALDI-MS, i.e., surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS).…”

Section: Other Methodsmentioning

confidence: 99%

Nanobiotechnology as a platform for the diagnosis of COVID-19: a review

Abdelhamid

Badr

2021

Nanotechnol. Environ. Eng.

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A sensitive method for diagnosing coronavirus disease 2019 (COVID-19) is highly required to fight the current and future global health threats due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2). However, most of the current methods exhibited high false-negative rates, resulting in patient misdiagnosis and impeding early treatment. Nanoparticles show promising performance and great potential to serve as a platform for diagnosing viral infection in a short time and with high sensitivity. This review highlighted the potential of nanoparticles as platforms for the diagnosis of COVID-19. Nanoparticles such as gold nanoparticles, magnetic nanoparticles, and graphene (G) were applied to detect SARS-CoV 2. They have been used for molecular-based diagnosis methods and serological methods. Nanoparticles improved specificity and shorten the time required for the diagnosis. They may be implemented into small devices that facilitate the self-diagnosis at home or in places such as airports and shops. Nanoparticles-based methods can be used for the analysis of virus-contaminated samples from a patient, surface, and air. The advantages and challenges were discussed to introduce useful information for designing a sensitive, fast, and low-cost diagnostic method. This review aims to present a helpful survey for the lesson learned from handling this outbreak to prepare ourself for future pandemic.

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Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

Cited by 82 publications

References 448 publications

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis

Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples

Nanobiotechnology as a platform for the diagnosis of COVID-19: a review

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Nanoparticle-based surface assisted laser desorption ionization mass spectrometry: a review

Cited by 82 publications

References 448 publications

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO2 Sorption and Hydrogen Generation via NaBH4 Hydrolysis

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO2 Sorption and Hydrogen Generation via NaBH4 Hydrolysis

Light sheet fluorescence microscopy guided MALDI-imaging mass spectrometry of cleared tissue samples

Nanobiotechnology as a platform for the diagnosis of COVID-19: a review

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Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis

Salts Induced Formation of Hierarchical Porous ZIF‐8 and Their Applications for CO₂ Sorption and Hydrogen Generation via NaBH₄ Hydrolysis