“…Reports of an association between RV-C infection and severe respiratory disease have been mixed as some studies have found an association (Bizzintino et al, 2011;Bochkov et al, 2011;Camargo et al, 2012;Piralla et al, 2009) but others have not (Iwane et al, 2011;Linsuwanon et al, 2009). Similar to other acute viral respiratory tract infections where a correlation exists between viral load and disease severity (DeVincenzo et al, 2010;Li et al, 2010;Roussy et al, 2014;To et al, 2010), it is suspected that RV-C load may also drive disease severity.…”