2016
DOI: 10.1007/s13337-016-0319-7
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Human papillomavirus (HPV) infection: a Mozambique overview

Abstract: Human Papillomavirus is agent of the most common sexually transmitted disease which is able to infect mucosal and cutaneous membranes of the anogenital region, upper aerodigestive tract, and other head and neck mucosal regions. Although mainly HPV infection can be asymptomatic and transient, it may persist and give rise to various lesions such as warts, condyloma dysplasia and cancers depending on low or high risk type of HPV infection. Moreover, growing recent evidence suggests a role of this virus in male an… Show more

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Cited by 9 publications
(8 citation statements)
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“…However, when well-informed, 94% were favorable to the vaccination of their sons, what reinforces the need for educative interventions, for the diffusion of information regarding HPV, and for preventive measures. 10 In addition, the Brazilian Ministry of Health offers the cytopathological exam, whose main purpose is the early diagnosis of HPV in women between 25 and 59 years old. However, currently, Brazil does not reach its 80% goal for the target group, according to the World Health Organization (WHO).…”
Section: Introductionmentioning
confidence: 99%
“…However, when well-informed, 94% were favorable to the vaccination of their sons, what reinforces the need for educative interventions, for the diffusion of information regarding HPV, and for preventive measures. 10 In addition, the Brazilian Ministry of Health offers the cytopathological exam, whose main purpose is the early diagnosis of HPV in women between 25 and 59 years old. However, currently, Brazil does not reach its 80% goal for the target group, according to the World Health Organization (WHO).…”
Section: Introductionmentioning
confidence: 99%
“…3 , 21 , 22 For instance, various viral infections including HPV can disable the function of tumor suppressor proteins. 23 , 24 HPVs are divided into the low‐risk and high‐risk HPV types due to their oncogenic potential. 25 , 26 HPVs have various oncoproteins (eg, E6 and E7) that can interfere with cell cycle regulators.…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, HPV-related anogenital cancers are increasing worldwide with an estimation of new cases yearly of 13 000, 27 000 and 27 000 for vaginal, vulvar and AC, respectively [ 4 ]. Limited data are available on the impact of HPV and its associated diseases in Mozambique, attesting a high prevalence ranging from 40 to 96% depending on the considered population, and listed the most common and known risk factors, such as multiple sexual partners, reproductive age and other STD, including HIV [ 5 ]. A recent study on women aged 30–49 years showed a prevalence of HPV infection of 23.7% and women living with HIV were twice as likely to test positive for HPV as HIV negative women (39.2 vs. 19.9%) [ 6 ].…”
Section: Introductionmentioning
confidence: 99%