Human Papillomavirus Genotype Distribution among Thai Women with High-Grade Cervical Intraepithelial Lesions and Invasive Cervical Cancer: a Literature Review

Abstract

Asian Pac J Cancer Prev, 16 (13), [5153][5154][5155][5156][5157][5158] IntroductionMore than 90% of worldwide estimated human papillomavirus (HPV)-related cancer mortalities are secondary to invasive cervical cancer (Cutts et al., 2007). There are sufficient evidences to conclude that cervical cancer are virtually caused by complicated infection with high-risk (HR) or carcinogenic types of HPV. According to the recent classification proposed by the International Agency for Research on Cancer, twelve HR-HPV genotypes including type 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 are classified as one of 114 agents that are carcinogenic to human, or the so-called "group A" (IARC, 2006).As a substantial geographical variation in the HPV genotype distribution has been observed (Li et al., 2011), data regarding HPV type-specific prevalence in each country are therefore mandatory for providing baseline information to predict how the genotype-specific HPV vaccination and HPV-based screening will influence cervical cancer prevention. Accordingly, we evaluated the

<p>Sexual behavior and infection with cervical human papillomavirus types 16 and 18</p>

“…Almost all cases of cervical cancer can be attributed to infection with high-risk HPV 1,2. The risk of developing cervical precancerous lesion or cervical cancer, however, varies widely by HPV type, with types16 and 18 being associated with by far the highest risk 2–6…”

Prevalence of Cervical Intraepithelial Neoplasia (CIN) at Khulna Division of Bangladesh

“…Treatment received were periodic screening after 5 year 1188(96.9%), LEEP 18(1.8%), Cold coagulation 25(2.1%), and admission in Oncology department 1(.1%)( Table 7) 12 HPV geno type distribution showed considerable variation globally . 13 However PCR based HPV typing is not feasible in mass screening 14 . Many researches have focused on HPV types, scope of prophylactic and therapeutic vaccines, improve effectiveness of screening that was found in ATHENA trail, even then periodic screening needs to be continued.…”

Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus

“…Certainly, the possibility that the higher prevalence observed in some studies and the low prevalence in our case may be a result of variable methodology stringencies cannot be completely excluded. Whether the similarity of HPV infection rates and the citing of HPV16 as the most prevalent type in cervical cancers in Malaysia and its South‐East Asian neighbors is any indication of a similar pattern of community exposure and transmission that will translate into a similar low prevalence of HPV in ESCC among South‐East Asians needs to be determined.…”