Human Ovarian Tissue Cryopreservation as Fertility Reserve

Albani, Elena; Bracone, G.; Biccari, Sonia Di; Vitobello, Domenico; Fattizzi, N.; Levi-Setti, Paolo Emanuele

doi:10.5772/22644

Cited by 3 publications

(1 citation statement)

References 54 publications

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“…Cryopreservation of ovarian tissue can also be a method for women who have hormone-sensitive malignancies, and for women anticipating haematopoietic stem cell transplantation for the treatment of benign haematological diseases (sickle cell anaemia, thalassemia major, aplastic anaemia) [ 16 ].…”

Section: Fertility Preservationmentioning

confidence: 99%

Reproduction in premature ovarian insufficiency patients – from latest studies to therapeutic approach

Męczekalski¹,

Maciejewska-Jeske²,

Podfigurna³

2018

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Normal function of the ovaries, which is responsible for the hormonal and reproductive processes, is one of the most important determinants of fertility. Premature ovarian insufficiency (POI) is defined as cessation of menstrual cycle, increased serum follicle-stimulating hormone (FSH) levels, and decrease serum oestradiol levels in women before the age of 40 years. POI concerns about 1% of women and is characterised by severely diminished fertility. For the POI patient, this is one of the most dramatic problems. It influences their psychological status and functioning in society. The chance for spontaneous conception is very limited and ranges from 4 to 8%. For contemporary medicine, infertility treatment in POI patients is a challenge. The problem is that there are no effective therapies to augment ovarian activity in POI patients. At present, oocyte donation is regarded as the only proven method in the treatment of infertility in POI patients. However, nowadays we can observe important progress in the development of fertility preservation methods. In the POI field it refers to cryopreservation of oocytes, embryos, and ovarian tissue. Additionally, new methods known as in vitro activation of dormant follicles and possible use of stem cells should be mentioned.

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Section: Fertility Preservationmentioning

confidence: 99%

Reproduction in premature ovarian insufficiency patients – from latest studies to therapeutic approach

Męczekalski¹,

Maciejewska-Jeske²,

Podfigurna³

2018

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Ovarian tissue cryopreservation: a committee opinion

2014

Fertility and Sterility

206

106

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Ovarian tissue cryopreservation is an option to preserve reproductive potential in patients who must urgently undergo aggressive chemotherapy and/or radiotherapy or who have other medical conditions requiring treatment that may threaten ovarian function and subsequent fertility. Ovarian tissue cryopreservation may be the only option available to prepubertal girls undergoing such treatments. However, these techniques are still considered to be experimental. This document outlines the current technology, clinical outcomes, and risks of ovarian tissue cryopreservation and recommendations for clinical applications. This document and the document "Mature Oocyte Cryopreservation: A Guideline" published in 2013 (Fertil Steril 2013;99:37-43) replace the document "Ovarian Tissue and Oocyte Cryopreservation" last published in 2008 (Fertil Steril 2008;90:S241-6).

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Fertility preservation: Ovarian tissue cryopreservation (OTC) revisited

Talwar

2016

Fertil Sci Res

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Human Ovarian Tissue Cryopreservation as Fertility Reserve

Cited by 3 publications

References 54 publications

Reproduction in premature ovarian insufficiency patients – from latest studies to therapeutic approach

Reproduction in premature ovarian insufficiency patients – from latest studies to therapeutic approach

Ovarian tissue cryopreservation: a committee opinion

Fertility preservation: Ovarian tissue cryopreservation (OTC) revisited

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