Human Infection with<i>Rickettsia honei</i>, Thailand

Jiang, Ju; Sangkasuwan, Vichai; Lerdthusnee, Kriangkrai; Sukwit, Suchitra; Chuenchitra, Thippawan; Rozmajzl, Patrick J.; Eamsila, Chirapa; Jones, James W.; Richards, Allen L.

doi:10.3201/eid1109.050011

Cited by 49 publications

(29 citation statements)

References 14 publications

(12 reference statements)

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“…72 Cases of human infection with this species have also been reported in Thailand, where the vector is Ixodes granulatus. 73 In Nepal, the same tick species has been suggested as a possible vector, together with Rhipicephalus haemaphysaloides, as seen in a case published in 2011. 72 In Eastern Australia, during 2003, a genetically related species of R. honei (marmionii strain) was isolated in patients with fever and headache.…”

Section: Rickettsia Honei Infectionmentioning

confidence: 89%

Syndromic classification of rickettsioses: an approach for clinical practice

Faccini-Martínez

García‐Álvarez

Hidalgo

et al. 2014

International Journal of Infectious Diseases

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Rickettsioses share common clinical manifestations, such as fever, malaise, exanthema, the presence or absence of an inoculation eschar, and lymphadenopathy. Some of these manifestations can be suggestive of certain species of Rickettsia infection. Nevertheless none of these manifestations are pathognomonic, and direct diagnostic methods to confirm the involved species are always required. A syndrome is a set of signs and symptoms that characterizes a disease with many etiologies or causes. This situation is applicable to rickettsioses, where different species can cause similar clinical presentations. We propose a syndromic classification for these diseases: exanthematic rickettsiosis syndrome with a low probability of inoculation eschar and rickettsiosis syndrome with a probability of inoculation eschar and their variants. In doing so, we take into account the clinical manifestations, the geographic origin, and the possible vector involved, in order to provide a guide for physicians of the most probable etiological agent.

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Section: Rickettsia Honei Infectionmentioning

confidence: 89%

Syndromic classification of rickettsioses: an approach for clinical practice

Faccini-Martínez

García‐Álvarez

Hidalgo

et al. 2014

International Journal of Infectious Diseases

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“…and Rhipicephalus sp. larval ticks from Rattus rattus trapped in Chiangmai Province, Thailand, in 1962 and has recently been determined to be a strain of R. honei (428). This discovery significantly enlarged the geographical distribution of this pathogenic rickettsia.…”

Section: Tick-borne Rickettsiae In Asia Species Identified As Pathogensmentioning

confidence: 95%

“…The rickettsiosis is generally mild, with symptoms such as fever, myalgia, headache, cough, and rash (2). Although R. honei was first discovered in Australia, it was subsequently described in Thailand (428) and, most recently, Nepal (430). The tick vector for R. honei in Australia is Bothriocroton hydrosauri, previously known as Aponomma hydrosauri (451).…”

Section: Species Identified As Pathogensmentioning

confidence: 99%

Update on Tick-Borne Rickettsioses around the World: a Geographic Approach

et al. 2013

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SUMMARY Tick-borne rickettsioses are caused by obligate intracellular bacteria belonging to the spotted fever group of the genus Rickettsia . These zoonoses are among the oldest known vector-borne diseases. However, in the past 25 years, the scope and importance of the recognized tick-associated rickettsial pathogens have increased dramatically, making this complex of diseases an ideal paradigm for the understanding of emerging and reemerging infections. Several species of tick-borne rickettsiae that were considered nonpathogenic for decades are now associated with human infections, and novel Rickettsia species of undetermined pathogenicity continue to be detected in or isolated from ticks around the world. This remarkable expansion of information has been driven largely by the use of molecular techniques that have facilitated the identification of novel and previously recognized rickettsiae in ticks. New approaches, such as swabbing of eschars to obtain material to be tested by PCR, have emerged in recent years and have played a role in describing emerging tick-borne rickettsioses. Here, we present the current knowledge on tick-borne rickettsiae and rickettsioses using a geographic approach toward the epidemiology of these diseases.

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“…In this regard, a single A. americanum was found positive for a Rickettsia that had 100% homology to R. honei ompB. R. honei is known to be a human pathogen in Australia and Thailand ( Jiang et al 2005b). Attempts to amplify additional gene targets (ompA and sca4) for this molecular isolate were unsuccessful.…”

Section: Public Health Implicationsmentioning

confidence: 96%

Bacterial Pathogens in Ixodid Ticks from a Piedmont County in North Carolina: Prevalence of Rickettsial Organisms

Smith

Ponnusamy

Jiang

et al. 2010

Vector-Borne and Zoonotic Diseases

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In North Carolina, reported human cases of tick-borne illness, specifically Rocky Mountain spotted fever, have escalated over the past decade. To determine the relative abundance of vectors and to estimate the risk of acquiring a tick-borne illness in peri-residential landscapes, ticks were collected in Chatham County, a typical Piedmont county and, samples of the ticks were tested for infection with selected bacterial pathogens using real-time quantitative polymerase chain reaction assays. Ticks (n = 3746) were collected by flagging vegetation at 26 sites from April to July 2006. The predominant questing tick was Amblyomma americanum (98.5%) with significantly fewer Dermacentor variabilis (1.0%) and Ixodes scapularis (0.5%) collected. Spotted fever group (SFG) rickettsiae were detected in 68.2% of 1590 A. americanum with 56.4% of the molecular isolates identified as Rickettsia amblyommii, an informally named member of the SFG rickettsiae. Comparatively, smaller numbers of A. americanum contained Ehrlichia chaffeensis (1.8%) and Borrelia lonestari (0.4%). Of 15 I. scapularis nymphs tested, 6 (40%) were positive for Borrelia burgdorferi sensu lato. Seven (19.4%) of 36 adult D. variabilis tested positive for Rickettsia montanensis, 4 (11.1%) were positive for R. amblyommii, and 5 (13.9%) were infected with unidentified species of SFG rickettsiae. The tick population in Chatham County contains a diverse array of microbes, some of which are known or potential pathogens. Highest attack rates would be expected from A. americanum ticks, and highest potential risk of infection with a tick-transmitted agent would be to rickettsial organisms, particularly R. amblyommii. Accordingly, longitudinal eco-epidemiology investigations are needed to determine the public health importance of A. americanum infected with rickettsial organisms.

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Human Infection withRickettsia honei, Thailand

Cited by 49 publications

References 14 publications

Syndromic classification of rickettsioses: an approach for clinical practice

Syndromic classification of rickettsioses: an approach for clinical practice

Update on Tick-Borne Rickettsioses around the World: a Geographic Approach

Bacterial Pathogens in Ixodid Ticks from a Piedmont County in North Carolina: Prevalence of Rickettsial Organisms

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