With growing urbanization, an increasing number of landslides worldwide are linked to construction works, especially along transportation routes. To get a better understanding of these post‐construction landslides at artificial waterways, archive studies have been conducted, in addition to analysis of historical scientific literature and technical reports. The resultant database is used to describe the occurrence and the characteristics of the landslides at the Mittelland Canal, and to evaluate aspects of conditioning and preparatory factors, potential triggers and applied mitigation measures. The Mittelland Canal has been chosen because it is one of the most important artificial waterways in Europe, and the high number of landslides that occur there is unique. In particular, landslides at the Mittelland Canal were frequently reported in the first half of the 20th century. The susceptibility to landslides is strongly influenced by material characteristics, as a large number of landslides is linked to sites where fine‐grained mudstone is abundant, which quickly decomposes under immersion in water or under dynamic stress. In addition, landslides can be linked to the creation of over‐steepened slopes. Construction works can also be considered another preparatory factor for landslides. In addition, some landslides in World War II appear to be connected to the blast of aerial bombings. Precipitation seems to play a minor role in triggering landslides. The applied mitigation measures were developed recently, marking the importance of the canal as a transportation route. © 2020 John Wiley & Sons, Ltd.