Human carriage of methicillin-resistant Staphylococcus aureus linked with pet dog

Cefai, C.; Ashurst, Stephen; Owens, Caroline

doi:10.1016/s0140-6736(94)91926-7

Cited by 146 publications

(94 citation statements)

References 2 publications

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“…Thus, only six pairs were indistinguishable by PFGE, although over 90 % of owners attending the veterinary clinic with the animal claimed to be the person having most contact with the dog. This again suggests that transfer between owner and dog, or vice versa, does occur, but may be more unusual than indicated by case reports [10][11][12][13]. The canine strains may have originated from other family members, but other sources, in particular veterinary practices, may be involved in the transfer of S. aureus to dogs.…”

Section: Discussionmentioning

confidence: 86%

“…Previous studies have reported isolation of MRSA from infected dogs [34,35], and case studies have shown that dogs of both infected patients and colonized subjects may be colonized with MRSA [10][11][12][13]. MRSA colonization has also been reported in healthy dogs belonging to healthy MRSA-negative members of veterinary clinic staff [35].…”

Section: Discussionmentioning

confidence: 99%

“…Although case reports of human infection or colonization from companion animals [10][11][12][13][14] have shown the potential of animals to act as reservoirs for transmission of MRSA [15], there appear to be no published reports on the prevalence of carriage of S. aureus in owners and their dogs. Reported rates of canine carriage vary widely, but higher levels reported in early studies may be due to the inability to distinguish between S. aureus and S. intermedius, the staphylococcal species most frequently isolated from dogs [15,16].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

2007

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SUMMARYCase reports have indicated transmission of Staphylococcus aureus between humans and pets. We investigated associations between level of contact between dog and owner, and S. aureus colonization. In a cross-sectional study, nasal carriage and antibiotic susceptibility of S. aureus was determined for 830 dogs and 736 owners. Relatedness of isolates was investigated using antibiograms and pulsed-field gel electrophoresis (PFGE). Associations between carriage and demographics or amount of contact between owners and dogs were documented. S. aureus was isolated in 24% of humans and 8 . 8% of dogs. Antibiotic resistance was significantly more common in canine isolates. Of 17 owner/dog colonized pairs, six were indistinguishable by PFGE. Colonization of dogs was not associated with close human contact, but was strongly associated with health-care occupations (OR 3 . 29, P=0 . 002). In outbreak situations health-care workers' pets should be considered as a source of S. aureus. High rates of resistance indicate increased monitoring of antibiotic use in veterinary practice is needed.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

2007

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“…Other studies have observed colonization of other family members [24,25] and even pets [26]. The factors which affect colonization are still poorly understood [27,28], although the role of lipoteichoic acid [29,30] and surface-associated proteins in the staphylococcal cell wall [31,32], as well as those binding to nasal mucin [33] have been investigated.…”

Section: Discussionmentioning

confidence: 99%

The prevalence and source of methicillin-resistant Staphylococcus aureus (MRSA) in the community in Hong Kong

O'Donoghue

Boost

2004

Epidemiol. Infect.

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SUMMARYAlthough reports of isolation of methicillin-resistant Staphylococcus aureus (MRSA) from patients admitted from the community have increased, few studies have investigated colonization of healthy subjects. This study aimed to determine community levels of MRSA in Hong Kong. Nasal swabs from a cross section of young adults and family units were cultured for MRSA. Antibiotic sensitivities and risk factors for carriage were determined and clonal relationships were investigated by pulsed-field gel electrophoresis (PFGE). Overall carriage was low (1 . 4%), and associated with health-care exposures (OR 13 . 56, 95 % CI 1 . 11-165 . 21). Subjects working in health care yielded multi-resistant MRSA strains, but isolates from non-hospital-exposed subjects were methicillin-resistant only. Strains indistinguishable by PFGE were carried by subjects working together, and some spread to other contacts was observed. MRSA colonization in the community is rare in Hong Kong and is largely associated with working in health care. Community-acquired staphylococcal infections may be treated with agents effective against methicillin-sensitive strains.

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“…However, the urban poor who did not have known MRSA risk factors had an MRSA prevalence similar to that of the general population (38). Household pets may also carry MRSA (151), and transmission to humans has been suspected (32). Reports on MRSA in the community are conflicting.…”

Section: Community-acquired Mrsamentioning

confidence: 99%