Human and animal leptospirosis in Southern Brazil: A five-year retrospective study

Jorge, Sérgio; Schuch, Rodrigo Andrade; Oliveira, Natasha Rodrigues de; Cunha, C. E.; Gomes, Charles; Oliveira, Thaís Larré; Rizzi, Caroline; Qadan, Aisha Farid; Pacce, Violetta Dias; Recuero, Ana Lúcia Coelho; Brod, Claudiomar Soares; Dellagostin, Odir A.

doi:10.1016/j.tmaid.2017.07.010

Cited by 25 publications

(26 citation statements)

References 45 publications

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“…These are further classified by serology into more than 300 different serovars of which more 250 are known to infect humans (2). Leptospirosis is strongly associated with environmental factors including heavy rainfall, flooding, population growth, poor sanitation and hygiene and disasters (3,4).…”

Section: Introductionmentioning

confidence: 99%

“…In addition, another factor contributing to the increased incidence of disease at country is the climate, in tropical zones the heat and humidity favors the transmission of Leptospira spp. (3). In Brazil, notification of human leptospirosis is mandatory and confirmed cases are reported in the databases, In the current study, we analyzed the incidence of human cases of leptospirosis in Brazil.…”

Section: Introductionmentioning

confidence: 99%

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Incidence analysis of human leptospirosis in Brazil

Silveira

Hartwig

McBride³

2020

VITTALLE, ISSN 1413-3563, Rio Grande, Brasil

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Leptospirosis is a neglected infectious disease that affects humans and animals with a higher incidence in the tropics and subtropics. In that context, the aim of this study was to describe the temporal distribution of the epidemiology and sociodemographic factors of human leptospirosis in Brazil. The analysis conducted in this study was based to age, gender, area, schooling, region and skin colour reported by Ministry of Health from National Disease Notification System (SINAN) and National Survey of Household Samples (PNAD) database of Brazil, during the period 2007 to 2014. A total of 22,889 cases were reported, the majority of which were registered in male and urban area, more than 70% and 80%, respectively. The greatest number of cases occur in patients with age group between 20-39 years. However, there was a significant increase in children between 0 and 9 (p = 2.8×10-7), 10 e 14 (p = 0.015) e 70 e 79 (p = 0.021) years old. The North region highlighted in relation to the other regions of the country, with a significant increase (p = 2.4×10-11) in the number of cases. An epidemiological surveillance of leptospirosis is important in Brazil once the incidence of disease is increasing in children and the elderly. We also show are essential efforts between medical and governmental institutions to improve the quality of data. Understand the disease trends can be providing insights into the prevention and control of leptospirosis in Brazil and others development countries. Análise da incidência de leptospirose humana no Brasil RESUMO Leptospirose é uma doença infecciosa negligenciada, que afeta humanos e animais com maior incidência nos países tropicais e subtropicais. Nesse contexto, o objetivo deste estudo foi descrever a tendência de análise temporal e fatores sociodemográficos da leptospirose em humana no Brasil. A análise realizada neste estudo foi baseada na idade, sexo, área, escolaridade, região e cor da pele. Os dados obtidos do Sistema Nacional de Notificação de Doenças (SINAN) organizado pelo Ministério da Saúde e do banco de dados da Pesquisa Nacional de Amostras de Domicílios (PNAD) do Brasil, durante no período de 2007 a 2014. Foram relatados 22.889 casos, sendo a maioria destes registrados em homens e em área urbana, mais de 70% e mais de 80% dos casos, respectivamente. O maior número de casos ocorreu em pacientes com faixa etária entre 20 e 39 anos. No entanto, houve um aumento significativo em crianças com idade entre 0 e 9 (p = 2.8×10 7), 10 e 14 (p = 0.015) e 70 e 79 (p = 0.021) anos. A região Norte se destacou em relação as demais regiões do país, com um aumento significativo dos casos (p = 2.4×10-11). A vigilância epidemiológica da leptospirose no Brasil é importante, uma vez que a incidência da doença está aumentando em crianças e idosos. Também mostramos que são necessários esforços essenciais entre instituições médicas e governamentais para melhorar a qualidade dos dados. A análise de tendência temporal da doença pode fornecer informações sobre a prevenção e controle da leptospirose no Brasi...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Incidence analysis of human leptospirosis in Brazil

Silveira

Hartwig

McBride³

2020

VITTALLE, ISSN 1413-3563, Rio Grande, Brasil

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“…Estes dados corroboram com o presente relato em que o paciente tratava-se de um cão macho de um ano e seis meses, apesar de alguns autores não encontrarem relação direta entre idade, sexo, raça e peso com a infecção por leptospiras (Knöpfler et al 2017). Há relatos de aumento da incidência da doença em épocas do ano mais quentes e no período de chuvas (Jorge et al, 2017), assim como relatos de cães infectados que tiveram contato com água contaminada (Hagiwara et al 2015), acordando com o relato em que o cão acometido parece ter sido infectado devido à água contaminada da chuva que entrou em contato.…”

Section: Discussionunclassified

Leptospirose canina: Relato de caso

Silva

Rodrigues²,

Santana³

et al. 2018

Pubvet

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Leptospirosis is a zoonosis of worldwide distribution that has the dog as an important host, showing the importance of diagnosing and treating this animal that has a straight relationship with humans. A dog was attended at the Veterinary Hospital of the Federal University of Piauí in Teresina, Piauí, was present with history of hematuria, hyporexia and lethargy. Physical examination revealed lethargy, oral, ocular and penile icteric mucosa, pain at abdominal palpation and pyrexia. Hematologic analysis revealed hypochromic macrocytic anemia, thrombocytopenia, leukocytosis due to neutrophilia, and an increase in urea, AST, ALT, alkaline phosphatase and bilirubin values. The microscopic serum agglutination test showed a reactive result of Leptospira interrogans serovar Australis at the 1: 100 titre. The animal was effectively treated with Ampicillin, Doxycycline and supportive therapy.

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“…Direct transmission is caused by direct contact between urine/blood/ organs of animals infected with leptospira bacteria through wounds on the skin, conjunctiva, mucous membranes of the mouth, or nose. This transmission often occurs because there is a pool of water and soil that has been contaminated by animal urine containing leptospira [14,15]. Meanwhile, indirect transmission occurs due to contact between the skin that is not wounded with water contaminated with mouse urine in a time long time [16].…”

Section: Main Findingsmentioning

confidence: 99%

Environmental Factors Related to Leptospirosis in Indonesia: A Systematic Review

Haq¹,

Anggraini²,

Masnarivan³

2020

Proceedings of the Third Andalas International Public Health Conference, AIPHC 2019, 10-11th October 2019, Padang, West Sumater

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Leptospirosis is a zoonosis of worldwide distribution, especially subtropical or tropical countries, including Indonesia. Therefore, it is important to know what environmental factors related to leptospirosis in Indonesia. This research is a systematic review of 9 eligible research journals that published in 2005-2019 in Indonesia. Journals are obtained from Science Direct, PubMed, and Garuda databases. A total of 4 studies examining the relationship between the existence of rats with leptospirosis cases, found that there was a statistically significant relationship. A total of 3 studies found that there was a statistically significant relationship between a pool of water with leptospirosis cases. Meanwhile, 2 out of 4 studies found that there was a significant relationship between poor sewer conditions and poor garbage conditions with leptospirosis cases. In conclusion, most studies found that the existence of rats, a pool of water, poor sewer conditions, and poor garbage conditions are significantly related to leptospirosis cases in Indonesia.

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Human and animal leptospirosis in Southern Brazil: A five-year retrospective study

Cited by 25 publications

References 45 publications

Incidence analysis of human leptospirosis in Brazil

Incidence analysis of human leptospirosis in Brazil

Leptospirose canina: Relato de caso

Environmental Factors Related to Leptospirosis in Indonesia: A Systematic Review

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